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@article{ART002192660},
author={유형진 and 이종하 and LEE SU KYUNG and SONG YUNG SUN},
title={Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2017},
volume={27},
number={1},
pages={1-17}

TY - JOUR
AU - 유형진
AU - 이종하
AU - LEE SU KYUNG
AU - SONG YUNG SUN
TI - Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice
JO - Journal of Korean Medicine Rehabilitation
PY - 2017
VL - 27
IS - 1
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 1
EP - 17
SN - 1229-1854
AB - ObjectivesThis study aimed to investigate the effect of Bangkibokryeong-tang (BBT, Fangjifuling-tang) on blood glucose and body fat in high-fat diet-induced obese mice.MethodsThe experimental animals were divided into five groups- normal diet-fed control (ND), high-fat diet-fed control (HFD), HFD+BBT 75, HFD+BBT 150, and HFD+olistat as a positive drug control group. Markers of obesity, such as body weight, organ weight, diet ef-ficiency, and serum levels of total cholesterol, triglycerides, lipid content, leptin, adipo-nectin, glutamic oxaloacetic transaminase (GOT)/glutamic pyruvic transferase (GPT)/lactate dehydrogenase (LDH), blood glucose, and insulin, were measured. Furthermore, results of the oral glucose tolerance test and α-glucosidase inhibition activity were examined in obese mice.ResultsMice treated with BBT demonstrate lower body and organ weight, and reduced weight gain and food efficiency than that in the HFD-only control group. In addition, BBT decreased lipid accumulation in the liver and the levels of enzymes such as GOT, GPT, and LDH in the serum. Furthermore, the levels of triglycerides, total cholesterol, low density lip-oprotein (LDL), and leptin were decreased in the serum but the levels of high density lip-oprotein (HDL) and adiponectin were increased in the BBT-treated group compared with the control group. The BBT-treated group also demonstrated decreased blood glucose and in-sulin concentrations induced by feeding on a high-fat diet and improved glucose tolerance.ConclusionsBased on the results above, BBT may reduce body fat and hyperglycemia in HFD-induced obesity. This suggests that BBT may be clinically useful in the treatment of obesity. (J Korean Med Rehabil 2017;27(1):1-17)
KW - Bangkibokryeong-tang;Obesity;High fat diet;Hyperglycemia
DO -
UR -
ER -

유형진, 이종하, LEE SU KYUNG and SONG YUNG SUN. (2017). Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice. Journal of Korean Medicine Rehabilitation, 27(1), 1-17.

유형진, 이종하, LEE SU KYUNG and SONG YUNG SUN. 2017, "Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice", Journal of Korean Medicine Rehabilitation, vol.27, no.1 pp.1-17.

유형진, 이종하, LEE SU KYUNG, SONG YUNG SUN "Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice" Journal of Korean Medicine Rehabilitation 27.1 pp.1-17 (2017) : 1.

유형진, 이종하, LEE SU KYUNG, SONG YUNG SUN. Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice. 2017; 27(1), 1-17.

유형진, 이종하, LEE SU KYUNG and SONG YUNG SUN. "Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice" Journal of Korean Medicine Rehabilitation 27, no.1 (2017) : 1-17.

유형진; 이종하; LEE SU KYUNG; SONG YUNG SUN. Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice. Journal of Korean Medicine Rehabilitation, 27(1), 1-17.

유형진; 이종하; LEE SU KYUNG; SONG YUNG SUN. Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice. Journal of Korean Medicine Rehabilitation. 2017; 27(1) 1-17.

유형진, 이종하, LEE SU KYUNG, SONG YUNG SUN. Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice. 2017; 27(1), 1-17.

유형진, 이종하, LEE SU KYUNG and SONG YUNG SUN. "Effects of Bangkibokryeong-tang (Fangjifuling-tang) on the Reduction of Blood Glucose and Body Fat in High Fat Diet Induced Obese Mice" Journal of Korean Medicine Rehabilitation 27, no.1 (2017) : 1-17.