Pathological Laughing and Crying following Midbrain Infarction: Case Report and Literature Review (중뇌 경색 이후 발생한 병적 웃음과 울음 환자: 증례 보고 및 문헌 고찰)

So Ri Moon (문소리); Seo Hyun Park (박서현); Sunjoo An (안선주); Dongho Keum (금동호)

doi:10.18325/jkmr.2018.28.4.103

Pathological Laughing and Crying following Midbrain Infarction: Case Report and Literature Review

Journal of Korean Medicine Rehabilitation
Abbr : JKMR
2018, 28(4), pp.103-112
DOI : 10.18325/jkmr.2018.28.4.103
Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
Research Area : Medicine and Pharmacy > Korean Medicine
Received : September 15, 2018
Accepted : October 1, 2018
Published : October 31, 2018

So Ri Moon ¹, Seo Hyun Park ¹, Sunjoo An ¹, Dongho Keum ¹

¹동국대학교 분당한방병원 한방재활의학과

Accredited

ABSTRACT

Pathological laughing and crying (PLC) is a condition defined by relatively uncontrollable episodes of laughter, crying or both. PLC is an uncommon symptom usually caused by cerebral lesions. Midbrain involvement causing PLC is extremely unusual and the exact mechanism by which this condition develops is poorly understood. We recently experienced a 51-year-old woman who were diagnosed as PLC after midbrain infarction. She was treated by acupuncture, pulsed electromagnetic therapy (PEMT). After 6 weeks treatment, Pathological Laughter and Crying Scale (PLACS), Korean version of the Scale for the Assessment and Rating of Ataxia (K-SARA) are decreased and Korean version of Modified Barthel Index (K-MBI) is increased. Treatment of traditional Korean Medicine could be effective for stoke rehabilitation including post-stroke PLC. And we have considered mechanism of PLC associated with midbrain lesion, dysfunction of cortex-thalamus-hypothalamus-basal ganglia-mesencephalon and faciorespiratory nuclei pathways, cerebro-ponto-cerebellar pathways and damaged serotonergic neurotransmission can cause this based on recent neurobiology of emotion. To define exact mechanism and find effective treatment, further studies are needed. (J Korean Med Rehabil 2018;28(4):103-112)

KEYWORDS

Pathological laughing and crying, Midbrain infraction, Acupuncture, Pulsed electromagnetic therapy

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Journal of Korean Medicine Rehabilitation 2023 KCI Impact Factor : 0.6

Pathological Laughing and Crying following Midbrain Infarction: Case Report and Literature Review

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* References for papers published after 2023 are currently being built.

Journal of Korean Medicine Rehabilitation 2023 KCI Impact Factor : 0.6

Pathological Laughing and Crying following Midbrain Infarction: Case Report and Literature Review

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