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Epigenetic Modification in Chronic Pain: A Literature Review

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2020, 30(1), pp.63-78
  • DOI : 10.18325/jkmr.2020.30.1.63
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : December 14, 2019
  • Accepted : December 31, 2019
  • Published : January 31, 2020

Eun-mo Song 1 Hong Seok Cho 2 Kim Koh-Woon 1 Park Hi-Joon 1 Mi-Yeon Song 1

1경희대학교
2경희대학교 한의과대학 한방재활의학과교실

Accredited

ABSTRACT

Objectives To review the epigenetic modifications involved in chronic pain and to improve individualized intervention for the chronic pain. Methods Focused literature review. Results Significant laboratory and clinical data support that epigenetic modifications have a potential role for development of chronic pain. Conclusions Epigenetic approach may identify mechanisms critical to the development of chronic pain after injury, and may provide new pathways and target mechanisms for future treatment and individualized medicine. (J Korean Med Rehabil 2020; 30(1):63-78)

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