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Effects of Dioscoreae Rhizoma on Excercise Practice Ability and Blood Fatigue Variable Factor

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2020, 30(2), pp.37-46
  • DOI : 10.18325/jkmr.2020.30.2.37
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : March 16, 2020
  • Accepted : April 4, 2020
  • Published : April 30, 2020

Na-Ri Park 1 Yun-Jin Lee 1 Eun-Byeol Lee 1 Doo-Hwa Yang 2 Chang-Hoon Woo 1 Hee Duk An 1

1대구한의대학교
2대구한의대학교부속대구한방병원

Accredited

ABSTRACT

Objectives In this study, we analyzed the effect of Dioscoreae Rhizoma on exercise practice ability and blood fatigue variable factor in the forced swimming test. Methods Male mice were divided into four group. Mice were administrated with saline, Discorae Rhizoma extracted by water (DRW), Discorae Rhizoma extracted by 30% ethanol (DRE), red ginseng (RG), orally once per day, for 1 week. Exercise performance was evaluated by exhaustive swimming time and weights. Glycogen contents of liver and soleus muscle were measured at the end of the experiment. In addition, the biochemical parameters such as asparate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen, creatine, lactate dehydrogenase (LDH), ammonia, triglycerides (TG), total cholesterol (TC) and free fatty acid (FFA) were analyzed. Results Both DRW and DRE showed an improvement of swimming endurance compared with control group. Levels of ALT, ammonia, TG, TC and FFA were significantly decreased in both DRW and DRE compared with control group. Levels of AST, Creatine were significantly reduced in DRE group compared with control group. Moreover LDH showed only a tendency to increase in the DRW and DRE groups. Conclusions In summary, the present study showed that Dioscoreae Rhizoma improved in physical fatigue and exercise practice ability and DRE improved the superior than those of DRW. (J Korean Med Rehabil 2020;30(2):37-46)

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