@article{ART002611840},
author={Ji Hoon Kim and Sun Gil Kim and Joo Il Kim and Chan Suk Yoon and Ji Min Choi and Na Changsu and Kim Seon Jong},
title={The Effects of ChondroT on Thrombus in FeCl3-induced Rats},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2020},
volume={30},
number={3},
pages={45-56},
doi={10.18325/jkmr.2020.30.3.45}
TY - JOUR
AU - Ji Hoon Kim
AU - Sun Gil Kim
AU - Joo Il Kim
AU - Chan Suk Yoon
AU - Ji Min Choi
AU - Na Changsu
AU - Kim Seon Jong
TI - The Effects of ChondroT on Thrombus in FeCl3-induced Rats
JO - Journal of Korean Medicine Rehabilitation
PY - 2020
VL - 30
IS - 3
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 45
EP - 56
SN - 1229-1854
AB - Objectives This study was designed to investigate the effects of ChondroT on thrombus in FeCl3-induced rats.
Methods We exposed FeCl3 to rat’s carotid artery to induce thrombus. Specimens were divided in 5 groups; Intact, Control, ASA10 (aspirin 10 mg/kg), CT100 (ChondroT 100 mg/kg), and CT200 (ChondroT 200 mg/kg), each n=6. We investigated thromboxane, platelet activating factor (PAF), histological change, lipid metabolism, transaminase, leukocyte, erythrocyte and thrombocyte level.
Results In ASA10, CT200 groups, there was significants decrease in both thromboxane level and total cholesterol level, compared to control group and there were significant histological changes of blood vessel, compared to control group. In CT200 group, there was significant decrease in PAF level, compared to control group (p<0.05). In ASA10, CT200 groups, triglycerides level tended to decrease, compared to control group.
Conclusions Based on these results, it could be suggested that ChondroT was effective on thrombus in FeCl3-induced rats, and further study is needed to conduct a rigorous clinical research. (J Korean Med Rehabil 2020;30(3):45-56)
KW - ChondroT;Thrombosis;Herbal medicine;FeCl3
DO - 10.18325/jkmr.2020.30.3.45
ER -
Ji Hoon Kim, Sun Gil Kim, Joo Il Kim, Chan Suk Yoon, Ji Min Choi, Na Changsu and Kim Seon Jong. (2020). The Effects of ChondroT on Thrombus in FeCl3-induced Rats. Journal of Korean Medicine Rehabilitation, 30(3), 45-56.
Ji Hoon Kim, Sun Gil Kim, Joo Il Kim, Chan Suk Yoon, Ji Min Choi, Na Changsu and Kim Seon Jong. 2020, "The Effects of ChondroT on Thrombus in FeCl3-induced Rats", Journal of Korean Medicine Rehabilitation, vol.30, no.3 pp.45-56. Available from: doi:10.18325/jkmr.2020.30.3.45
Ji Hoon Kim, Sun Gil Kim, Joo Il Kim, Chan Suk Yoon, Ji Min Choi, Na Changsu, Kim Seon Jong "The Effects of ChondroT on Thrombus in FeCl3-induced Rats" Journal of Korean Medicine Rehabilitation 30.3 pp.45-56 (2020) : 45.
Ji Hoon Kim, Sun Gil Kim, Joo Il Kim, Chan Suk Yoon, Ji Min Choi, Na Changsu, Kim Seon Jong. The Effects of ChondroT on Thrombus in FeCl3-induced Rats. 2020; 30(3), 45-56. Available from: doi:10.18325/jkmr.2020.30.3.45
Ji Hoon Kim, Sun Gil Kim, Joo Il Kim, Chan Suk Yoon, Ji Min Choi, Na Changsu and Kim Seon Jong. "The Effects of ChondroT on Thrombus in FeCl3-induced Rats" Journal of Korean Medicine Rehabilitation 30, no.3 (2020) : 45-56.doi: 10.18325/jkmr.2020.30.3.45
Ji Hoon Kim; Sun Gil Kim; Joo Il Kim; Chan Suk Yoon; Ji Min Choi; Na Changsu; Kim Seon Jong. The Effects of ChondroT on Thrombus in FeCl3-induced Rats. Journal of Korean Medicine Rehabilitation, 30(3), 45-56. doi: 10.18325/jkmr.2020.30.3.45
Ji Hoon Kim; Sun Gil Kim; Joo Il Kim; Chan Suk Yoon; Ji Min Choi; Na Changsu; Kim Seon Jong. The Effects of ChondroT on Thrombus in FeCl3-induced Rats. Journal of Korean Medicine Rehabilitation. 2020; 30(3) 45-56. doi: 10.18325/jkmr.2020.30.3.45
Ji Hoon Kim, Sun Gil Kim, Joo Il Kim, Chan Suk Yoon, Ji Min Choi, Na Changsu, Kim Seon Jong. The Effects of ChondroT on Thrombus in FeCl3-induced Rats. 2020; 30(3), 45-56. Available from: doi:10.18325/jkmr.2020.30.3.45
Ji Hoon Kim, Sun Gil Kim, Joo Il Kim, Chan Suk Yoon, Ji Min Choi, Na Changsu and Kim Seon Jong. "The Effects of ChondroT on Thrombus in FeCl3-induced Rats" Journal of Korean Medicine Rehabilitation 30, no.3 (2020) : 45-56.doi: 10.18325/jkmr.2020.30.3.45