2010, Vol.10, No.1

Journal of Korean Medicine for Obesity Research 2023 KCI Impact Factor : 0.43

pISSN : 1976-9334 / eISSN : 2288-1522
https://journal.kci.go.kr/jkomor

Objectives The clinical trial was designed to investigate the safety and effects of Bofu-tsusho-san extracts on the change of the weight, body compositions, serum in obese patients. Methods This study was a 4-weeks, double blind, comparative clinical trial. Eligible subjects had a body mass index(BMI) greater than 25 kg/m² and waist circumference(WC) longer than 85 cm in woman or 90 cm in man. Among 38 subjects, 36 subjects were randomized either to Bofu-tsusho-san or placebo. After 4 weeks of treatment, we measured anthropometric factors(weight, height, WC, BMI etc.), abdominal fat area by CT scanning, serum lipid(total cholesterol(TC), triglyceride(TG), HDL cholesterol, LDL cholesterol), blood level of variety(glucose,adiponectine, leptin, C-reactive protein(CRP) etc.), blood pressure(BP). Adverse events also evaluated. Results BMI, BP, TG, CRP were reduced and weight, WC, score of KOQOL(Korean version of obesity-related QOL scale), SRI(Stress response inventory) were significant changed in Bofu-tsusho-san. But there were no considerable difference between Bofu-tsusho-san and placebo. there were no serious adverse events in either group. Conclusion There were limitations in this study that it conducted within a short period of 4 weeks. but its weight and WC loss effect was significant and it had few adverse events.

Objectives It is significant to determine the validation of a self-administered somatotype drawing for the simple assessment of childhood obesity in elementary school and clinical practice. Methods The subjects were 202 children(112 boys and 90 girls) who answered a questionnaire for somatotype drawing and weremeasured for body components with bioelectrical impedance. The somatotype drawing of children was analysed according to the three criteria of childhood obesity - BMI percentile,obesity index and percent body fat, respectively. Results BMI, waist-hip ratio, skeletal musclemass and proteinmass had significant differences(p<.05) between boys and girls. Somatotype drawing had the highest correlation with BMI in both boys and girls, and also showed a high correlation with BMI percentile, obesity index and percent body fat. According to these criteria of childhood obesity, the somatotype drawing was the best consistent with the obesity index, next turn was the percent body fat and then the BMI percentile. Conclusions The validation of somatotype drawing for the assessment of childhood obesity was analysed according to BMI percentile, obesity index and percent body fat, and the somatotype drawing was the best consistent with obesity index in both boys and girls.

Objective The aim of this study was to evaluate the influence of Gamitaeeumjowi-tang(GTT) prescribed by doctors of korean(KMD) medicine on liver function. Methods For this single-center, prospective, observational study, we enrolled patients who wished to take GTT prescribed by KMD for losing weight. sixty(60) patients took GTT for 33.8 days and completed questionnaires. Liver function tests(LFTs) were performed bofore(first test) and after each GTT treatment(finish test). For LFT, T-bil, ALP, AST, ALT were measured. Result There were no significant changes in LFT data between the first and finish tests. At first test, levels of test seven(7) patients were more than twice of normal range of upper limit, levels of eight(8) patients were more than normal range of upper limit, less than twice of normal range of upper limit. At last test, levels of nine(9) patients were more than normal range of upper limit, less than twice of normal range of upper limit. Conclusion The current study showed that ingestion of GTT prescribed by KMD did not increase the frequency of abnormal LFTs, at least in the short term.