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@article{ART001512603},
author={이지은 and SONG YUN KYUNG and Lim Hyung Ho},
title={Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients},
journal={Journal of Korean Medicine for Obesity Research},
issn={1976-9334},
year={2010},
volume={10},
number={1},
pages={1-16}

TY - JOUR
AU - 이지은
AU - SONG YUN KYUNG
AU - Lim Hyung Ho
TI - Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients
JO - Journal of Korean Medicine for Obesity Research
PY - 2010
VL - 10
IS - 1
PB - The Society of Korean Medicine for Obesity Research
SP - 1
EP - 16
SN - 1976-9334
AB - Objectives The clinical trial was designed to investigate the safety and effects of Bofu-tsusho-san extracts on the change of the weight, body compositions, serum in obese patients. Methods This study was a 4-weeks, double blind, comparative clinical trial. Eligible subjects had a body mass index(BMI) greater than 25 kg/m² and waist circumference(WC) longer than 85 cm in woman or 90 cm in man. Among 38 subjects, 36 subjects were randomized either to Bofu-tsusho-san or placebo. After 4 weeks of treatment, we measured anthropometric factors(weight, height, WC, BMI etc.), abdominal fat area by CT scanning, serum lipid(total cholesterol(TC), triglyceride(TG), HDL cholesterol, LDL cholesterol), blood level of variety(glucose,adiponectine, leptin, C-reactive protein(CRP) etc.), blood pressure(BP). Adverse events also evaluated. Results BMI, BP, TG, CRP were reduced and weight, WC, score of KOQOL(Korean version of obesity-related QOL scale), SRI(Stress response inventory) were significant changed in Bofu-tsusho-san. But there were no considerable difference between Bofu-tsusho-san and placebo. there were no serious adverse events in either group. Conclusion There were limitations in this study that it conducted within a short period of 4 weeks. but its weight and WC loss effect was significant and it had few adverse events.
KW - Obesity;Bofu-tsusho-san;Efficacy;Safety.
DO -
UR -
ER -

이지은, SONG YUN KYUNG and Lim Hyung Ho. (2010). Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients. Journal of Korean Medicine for Obesity Research, 10(1), 1-16.

이지은, SONG YUN KYUNG and Lim Hyung Ho. 2010, "Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients", Journal of Korean Medicine for Obesity Research, vol.10, no.1 pp.1-16.

이지은, SONG YUN KYUNG, Lim Hyung Ho "Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients" Journal of Korean Medicine for Obesity Research 10.1 pp.1-16 (2010) : 1.

이지은, SONG YUN KYUNG, Lim Hyung Ho. Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients. 2010; 10(1), 1-16.

이지은, SONG YUN KYUNG and Lim Hyung Ho. "Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients" Journal of Korean Medicine for Obesity Research 10, no.1 (2010) : 1-16.

이지은; SONG YUN KYUNG; Lim Hyung Ho. Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients. Journal of Korean Medicine for Obesity Research, 10(1), 1-16.

이지은; SONG YUN KYUNG; Lim Hyung Ho. Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients. Journal of Korean Medicine for Obesity Research. 2010; 10(1) 1-16.

이지은, SONG YUN KYUNG, Lim Hyung Ho. Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients. 2010; 10(1), 1-16.

이지은, SONG YUN KYUNG and Lim Hyung Ho. "Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients" Journal of Korean Medicine for Obesity Research 10, no.1 (2010) : 1-16.