본문 바로가기
  • Home

A Study on the Acute Toxicity of Fermented Bangpungtongsung-san(Fangfengtongsheng-san) Extract in ICR Mice

  • Journal of Korean Medicine for Obesity Research
  • Abbr : J Korean Med Obes Res
  • 2009, 9(2), pp.11-19
  • Publisher : The Society of Korean Medicine for Obesity Research
  • Research Area : Medicine and Pharmacy > Korean Medicine

이지혜 1 이재훈 1 엄영란 1 마진열 1

1한국한의학연구원

Candidate

ABSTRACT

Objectives In this study, we investigated the acute toxicity and safety about fermented Bangpungtongsung-san(Fangfengtongsheng-san) extract. Methods To evaluate the acute toxity and safety, fermented Bangpungtongsung-san (Fangfengtongsheng-san) at the respective doses of 0(control group), 1250, 2500 and 5000 ㎎/㎏ were orally treated to 20 male and 20 female mice. After single administration, we observed survival rates, general toxicity, changes of body weight and autopsy. Results Compared with the control group, we could not find any toxic alteration in all treated groups (1250, 2500 and 5000 ㎎/㎏). Conclusions LD50 of fermented Bangpungtongsung-san(Fangfengtongsheng-san) extract might be over 5000 ㎎/㎏ and it is very safe to ICR mice.

Citation status

* References for papers published after 2023 are currently being built.