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@article{ART002424303},
author={Min-Ju Kim and 김현숙 and Kim Ae-Jung},
title={Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome},
journal={Journal of Korean Medicine for Obesity Research},
issn={1976-9334},
year={2018},
volume={18},
number={2},
pages={83-95},
doi={10.15429/jkomor.2018.18.2.83}

TY - JOUR
AU - Min-Ju Kim
AU - 김현숙
AU - Kim Ae-Jung
TI - Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome
JO - Journal of Korean Medicine for Obesity Research
PY - 2018
VL - 18
IS - 2
PB - The Society of Korean Medicine for Obesity Research
SP - 83
EP - 95
SN - 1976-9334
AB - Objectives: The aim of this study was optimized mixing ratio of mulberry leaf, mulberry fruit, and silkworm for amelioration of the metabolic syndrome by using response surface method (RSM). Methods: Antioxidant, antidiabetic and antihypertensive activities of fifteen mixed powder of mulberry leaf, mulberry fruit, and silkworm by RSM were measured as indicators of metabolic syndrome. Results: The optimal mixing ratio of mulberry leaves, mulberry fruits, and silkworm with the greatest antioxidant, antidiabetic and antihypertensive activities was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C). At this time, it was predicted that the total polyphenol content was estimated to be 185.51 tannic acid equivalent mg/g, 1, 1-diphenyl-2-picrylhy drazyl radical scavenging activity 84.77%, 1-deoxynojirimycin content 415.66 mg/100 g, α-glucosidase inhibitory activity 64.31%, γ-aminobutyric acid content 267.77 mg/100 g, potassium content 1,899.11 mg/100 g, and angiotensin-converting-enzyme inhibitory activity was estimated to be 73.78%. Conclusions: It was concluded that the significant effect of the mulberry leaf, mulberry fruit, and silkworm on the metabolic syndrome-related biological activity indices (antioxidant activity, antidiabetic activity and antihypertensive activity) was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C).
KW - Mulberry leaf;Mulberry fruit;Silkworm;Metabolic syndrome;Optimization;Response surface methodology (RSM)
DO - 10.15429/jkomor.2018.18.2.83
ER -

Min-Ju Kim, 김현숙 and Kim Ae-Jung. (2018). Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome. Journal of Korean Medicine for Obesity Research, 18(2), 83-95.

Min-Ju Kim, 김현숙 and Kim Ae-Jung. 2018, "Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome", Journal of Korean Medicine for Obesity Research, vol.18, no.2 pp.83-95. Available from: doi:10.15429/jkomor.2018.18.2.83

Min-Ju Kim, 김현숙, Kim Ae-Jung "Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome" Journal of Korean Medicine for Obesity Research 18.2 pp.83-95 (2018) : 83.

Min-Ju Kim, 김현숙, Kim Ae-Jung. Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome. 2018; 18(2), 83-95. Available from: doi:10.15429/jkomor.2018.18.2.83

Min-Ju Kim, 김현숙 and Kim Ae-Jung. "Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome" Journal of Korean Medicine for Obesity Research 18, no.2 (2018) : 83-95.doi: 10.15429/jkomor.2018.18.2.83

Min-Ju Kim; 김현숙; Kim Ae-Jung. Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome. Journal of Korean Medicine for Obesity Research, 18(2), 83-95. doi: 10.15429/jkomor.2018.18.2.83

Min-Ju Kim; 김현숙; Kim Ae-Jung. Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome. Journal of Korean Medicine for Obesity Research. 2018; 18(2) 83-95. doi: 10.15429/jkomor.2018.18.2.83

Min-Ju Kim, 김현숙, Kim Ae-Jung. Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome. 2018; 18(2), 83-95. Available from: doi:10.15429/jkomor.2018.18.2.83

Min-Ju Kim, 김현숙 and Kim Ae-Jung. "Optimization of Mixing Ratio of Mulberry Leaf, Mulberry Fruit, and Silkworm for Amelioration of Metabolic Syndrome" Journal of Korean Medicine for Obesity Research 18, no.2 (2018) : 83-95.doi: 10.15429/jkomor.2018.18.2.83