@article{ART002647712},
author={Kang Hye-ra and Yang Han-joon},
title={A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal},
journal={Kinesiology },
issn={2435-0702},
year={2019},
volume={4},
number={2},
pages={1-6}
TY - JOUR
AU - Kang Hye-ra
AU - Yang Han-joon
TI - A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal
JO - Kinesiology
PY - 2019
VL - 4
IS - 2
PB - Northeast Asian Studies Journal Institute (J-INSTITUTE)
SP - 1
EP - 6
SN - 2435-0702
AB - Although the inflammatory response is vital for biological regulation, chronic inflammation damages the human body. Presently available anti-inflammatory drugs, including steroids, have side effects that prevent their administration to athletes. This study aimed at elucidating a method to control exercise-induced inflammation and oxidative stress, by investigating the anti-inflammatory and antioxidant efficacy of extracts of Albizia julibrissin fermented with kefir yogurt(FKA) in vitro. We investigated the effect of FKA on RAW 264.7 cells using cell viability assays. The regulatory effect of FKA in lipopolysaccharide(LPS)-induced nitric oxide(NO) production was determined using Griess reagent and the reverse transcription polymerase chain reaction(RT-PCR) assays, with specific primers such as interleukin(IL)-1β, IL-6, and IL-10, inducible nitric oxide synthase(iNOS), and cyclooxygenase- 2(COX-2) in vivo. Furthermore, the 2,2-diphenyl-1-picrylhydrazyl(DPPH) radical scavenging assay was performed and the cellular morphology changes were observed using florescence microscopy. The results showed that FKA significantly reduced LPS–induced NO production by regulating the expression of IL-1β, iNOS, and COX-2; thus, FKA exerts cytoprotective effects against ROS-induced cell death. These data suggest the anti-inflammatory therapeutic potential of FKA.
KW - Albizia Julibrissin;Kefir;Anti-Inflammation;IL-1β;iNOS
DO -
UR -
ER -
Kang Hye-ra and Yang Han-joon. (2019). A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal. Kinesiology , 4(2), 1-6.
Kang Hye-ra and Yang Han-joon. 2019, "A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal", Kinesiology , vol.4, no.2 pp.1-6.
Kang Hye-ra, Yang Han-joon "A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal" Kinesiology 4.2 pp.1-6 (2019) : 1.
Kang Hye-ra, Yang Han-joon. A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal. 2019; 4(2), 1-6.
Kang Hye-ra and Yang Han-joon. "A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal" Kinesiology 4, no.2 (2019) : 1-6.
Kang Hye-ra; Yang Han-joon. A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal. Kinesiology , 4(2), 1-6.
Kang Hye-ra; Yang Han-joon. A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal. Kinesiology . 2019; 4(2) 1-6.
Kang Hye-ra, Yang Han-joon. A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal. 2019; 4(2), 1-6.
Kang Hye-ra and Yang Han-joon. "A SPORTS Nutrition Supplement, Albizia Julibrissin Extract Fermented with Kefir Yogut Regulates Lipopolysaccharideinduced Inflammatory Signal" Kinesiology 4, no.2 (2019) : 1-6.
