2011, Vol.18, No.1

Journal of Korean Society of Spine Surgery 2023 KCI Impact Factor : 0.03

pISSN : 2093-4378 / eISSN : 2093-4386
https://journal.kci.go.kr/krspine

Study Design : Experimental, prospective study Objectives : To examine the changes in the variable factors after an acute spinal cord injury(SCI) in rats and dogs simultaneously. Summary of Literature Review : No study has examined the variations of several factors in a SCI model in different species. Materials and Methods : In rats, a laminectomy was performed at the T10 level and the injured spinal cord was extracted. In Beagle dogs, the laminectomy level was T10 and T11. The motor function was evaluated using a modified Tarlov’s scale. A RT2 profiler PCR array was used to examine each factor (inflammatory cytokines, factors-related with apoptosis, neurotrophic factors, factors-related with extraceullar matrix). Results : IL-2, TNF, TNFRSF11B increased with time and showed no statistical difference between two species, but TNFSF13B showed a significant difference. BDNF decreased with time in both species, and GDNF was significantly lower in dogs. NGFβ, CTNF and its receptors showed no significant changes in the two species. MMP1 increased in both species but MMP7 decreased in rats and increased in dogs with time, and showed a significant difference between species. Conclusion : The change in inflammatory cytokines and extracellular matrix correlates with each factor in the combined patterns. Moreover, during the first week after SCI, inflammatory cytokines, apoptosis, neutrophic factors, and extracellular matrix factors may show a partial difference between experimental animals, which means that an animal model can be selected according to the particular experimental plan. Key Words : Spinal cord injury, Inflammatory cytokines, Factors-related with apoptosis, Neurotrophic factors, Factors-related with extraceullar matrix

Study Design: This is retrospective study. Objective: We evaluated the radiologic changes and quality of life after corrective osteotomy in kyphotic deformity of ankylosing spondylitis. Summary of Literature Review: There is few study about that relationship between corrective osteotomy and quality of life. Materials and Methods: Retrospective study about 16 patients who underwent corrective osteotomy from 2005 September to 2007 December was done. Radiologic assessments of sagittal balance were performed on the criteria of thoracic kyphosis, lumbar lordosis, distance between the vertical line on midpoint of C7 and posterosuperior point of S1 pre and postoperatively. Disease specific instruments: the Bath ankylosing spondylitis disease activity index (BASDAI) and the Bath ankylosing spondylitis functional index (BASFI)were applied. Clinical assessments were performed with short form-36 through interview and telephone. Results: The mean thoracic kyphosis was changed from 46.1 degrees to 39.3 degrees. The mean lumbar lordosis was corrected from - 7.4degrees to - 38.4 degrees, and the mean distance between vertical lines of C7 and S1 was improved from 127.1mm to 30mm. There were significant changes in the subgroup of Physical function, Role physical, Vitality, Social function, Role emotional, Mental health. (p<0.05)The changes of BASDAI, BASFI, Bodily pain and General health were not significant. And similar improvements in the radiological results and SF-36 scores were in the 6 patients with Andersson lesion. Conclusion: The parameters of radiographic assessment were improved after corrective osteotomy in the fixed kyphotic deformity of ankylosing spondylitis. General function, social function and mental health were also improved. Key Words: Ankylosing spondylitis, Corrective osteotomy, Quality of life

Study Design: A review of all presentations at the Korean Society of Spine Surgery(KSSS) congress from 2001 to 2005. Objectives: To determine the presentation to publication rate in peer-reviewed journals of abstracts presented at the KSSS congress and evaluate the consistency between the presented abstract and published full-text counterpart. Summary of Literature Review: The rate of publication for presentation at international meetings has been determined but there has been no study for the KSSS. Material and Methods: This study reviewed all podium presentations of the past KSSS Spring and Fall meetings from 2001 to 2005. A computer search for each abstract was performed. The final published journal, time to publication and publication rate were evaluated according to subspecialty. The published full-text article was compared with the original abstract and evaluated for consistency with respect to the author, material and method, and result. Results: A total of 288 free-papers were identified, of which 167 of them were published as full-text articles. The mean time to publication was 12.15 months. The publication rates according to the subspecialty were basic 67%, lumbar 68%, cervical 64%, deformity 50%, trauma 53%, minimal 14% and others 51%, respectively. Conclusion: The presentation to publication rate of the Korean society of spine surgery podium presentations was lower than other international meetings but the articles showed a high consistency rate. Key Word: Korean Society of Spine Surgery congress, Presentation, Publication