2016, Vol.23, No.2

Clinical Outcomes of a Zero Profile Implant for Single-Level Anterior Cervical Discectomy and Fusion

Dae Ho Ha , Sung Kyun Oh , Dae Moo Shim | 2016, 23(2) | pp.71~76 | number of Cited : 0

Factors Associated with Early Postoperative Complications in Patients with Cervical Spondylotic Myelopathy

Min Woo Kim , 서정호 , 이규열 | 2016, 23(2) | pp.77~83 | number of Cited : 0

Comparison of the Efficacy and Safety Profiles of a Pelubi Sustained Release Tab Versus a Pelubi Tab in Patients with Chronic Back Pain: A Randomized, Double - Blind, Multi - Institution Phase III Study

Ki-Tack KIM , KIM TAE KYUN , 최지웅 and 4 other persons | 2016, 23(2) | pp.84~92 | number of Cited : 0

Study Design: A randomized, double-blind, multi-institution, phase III study. Objectives: To evaluate the efficacy and safety of the Pelubi Sustained Release (SR) Tab in patients with chronic back pain, in comparison with the Pelubi Tab, whose efficacy has already been approved, a phase 3 clinical trial was conducted. Summary of Literature Review: The Pelubi Tab Has shown clinical efficacy in patients with back pain. Materials and Methods: From April 11, 2014 to July 24, 2014, 166 chronic back pain patients were recruited as subjects through a multi-institution, double-blind, random sample. We compared the experimental and control groups’ clinical efficacy, which was estimated by the 100-mm Pain Visual Analog Scale (VAS) after 28 days of medication. We also compared the treatment efficacy of both drugs by using a variation of the Oswestry Disability Index (ODI) and Physician Global Assessment (PGA), with the total usage of relief medicine. The side effects and clinical pathology were also noted. Results: Neither group showed a significant difference in 100-mm Pain VAS or ODI variation (p=0.1702, p=0.9041). There was no statistically significant difference between the experimental group and the control group in PGA or total usage of relief medicine. The ODI and PGA variation were not worse in the experimental group than the control group. The two groups showed no significant differences in side effects (p=0.9708). Conclusions: This study found that the Pelubi SR Tab applied to back pain patients was not inferior to the Pelubi Tab and did not show any significant difference in terms of safety. The Pelubi SR Tab can be used with the same expectation of safety as the Pelubi Tab. Materials and Methods: From April 11, 2014 to July 24, 2014, 166 chronic back pain patients were recruited as subjects through a multi-institution, double-blind, random sample. We compared the experimental and control groups’ clinical efficacy, which was estimated by the 100-mm Pain Visual Analog Scale (VAS) after 28 days of medication. We also compared the treatment efficacy of both drugs by using a variation of the Oswestry Disability Index (ODI) and Physician Global Assessment (PGA), with the total usage of relief medicine. The side effects and clinical pathology were also noted. Results: Neither group showed a significant difference in 100-mm Pain VAS or ODI variation (p=0.1702, p=0.9041). There was no statistically significant difference between the experimental group and the control group in PGA or total usage of relief medicine. The ODI and PGA variation were not worse in the experimental group than the control group. The two groups showed no significant differences in side effects (p=0.9708). Conclusions: This study found that the Pelubi SR Tab applied to back pain patients was not inferior to the Pelubi Tab and did not show any significant difference in terms of safety. The Pelubi SR Tab can be used with the same expectation of safety as the Pelubi Tab.

Radiographic and Clinical Outcomes of Posterior Interbody Fusion for High-Grade Spondylolisthesis

정재윤 , Hyoung-Yeon Seo , Kim Sung Kyu | 2016, 23(2) | pp.93~99 | number of Cited : 0

Study Design: Retrospective study. Objectives: To evaluate the clinical and radiological outcomes of posterior interbody fusion using pedicle screw fixation after posterior decompression for high-grade spondylolisthesis. Summary of Literature Review: The surgical treatment of high-grade spondylolisthesis has been controversial. However, few reports on the results of reduction and posterior interbody fusion after posterior decompression have been published. Materials and Methods: Thirteen patients with L5-S1 high-grade spondylolisthesis (Meyerding grade III, IV) who underwent reduction and posterior interbody fusion were analyzed with at least 2 years of follow-up. The mean age of the patients (male 2, female 11) was 51 years. Classified by the type of spondylolisthesis, 10 cases were isthmic, 2 cases dysplastic, and 1 case degenerative. A visual analogue scale (VAS), the Oswestry Disability Index (ODI) score, bone union, anterior slippage, and slip angle were used in comparing clinical and radiographic outcomes. Results: All cases showed improvement of preoperative symptoms. The VAS and ODI score improved from a mean of 8.9 points and 36.2 points preoperatively to 2.1 points and 10.2 points, respectively, at last follow-up. The degree of anterior slippage measured by Taillard’s method was improved from a mean of 57.7% before surgery to mean of 14.6% at last follow-up. The slip angle also changed from a mean of 2.4° kyphosis before surgery to a mean of 7.6° lordosis at last follow-up. There were two complications: infection and new radiating pain. Conclusions: Reduction and posterior interbody fusion using pedicle screw fixation after posterior decompression was a useful surgical method for high-grade spondylolisthesis that corrected lumbosacral kyphosis, filled the structural space of the anterior column, and acheived fusion of interbody movement.

Risk Factors of Cage Subsidence after Posterior Lumbar Interbody Fusion

Dong-Yeong Lee , Jeong Soon-Taek , Changhwa Hong and 3 other persons | 2016, 23(2) | pp.100~107 | number of Cited : 3

Study Design: Retrospective study. Objectives: The purpose of this study was to evaluate risk factors for subsidence after posterior lumbar interbody fusion (PLIF). Summary of Literature Review: Body mass index (BMI), bone mineral density (BMD), cage characteristics (titanium or poly-ether-etherketone (PEEK)) and degree of disc distraction are risk factors for cage subsidence after PLIF. Materials and Methods: From January 2010 to January 2015, a total of 69 patients (93 segments) who were diagnosed with degenerative lumbar spine disease at the current authors’ institution and underwent follow-up for at least 1 year were included in this retrospective study. Data on all factors related to cage subsidence were taken into consideration. The degree of association for each of the factors was determined through the calculation of odds ratios (ORs) with a 95% confidence interval. Logistic regression analyses were performed. The P-value that represented statistical significance was set below 0.05. Results: There were no significant associations between fused segment level and cage subsidence (p=0.588), nor were there any significant associations between the kind of cage (titanium or PEEK) and cage subsidence (p=0.371). Using logistic regression, the factors with a P-value below the 0.20 level in univariate analyses were included in the multivariate analyses. In multivariate analyses, diabetes mellitus (DM) (p=0.029, OR, 4.524), osteoporosis (p=0.026, OR, 6.046), and degree of disc distraction (p=0.010, OR, 1.446) had significant associations with cage subsidence. In addition, there were significant associations between cage subsidence and instrument failure (p=0.008, OR, 8.235). Conclusions: DM and osteoporosis, which may affect bony structures, have significant associations with cage subsidence after PLIF. Cage insertion with excessive disc distraction during surgery may also affect cage subsidence after PLIF.

Late Pyogenic Spondylitis after Vertebroplasty with PMMA - filled Adjacent Segments - A Case Report -

Eui-Sung Choi , 김용민 , 정수리 | 2016, 23(2) | pp.108~113 | number of Cited : 0

Spinopelvic Reconstruction with Femoral Allograft and Vertical Rectus Abdominis Myocutaneous Flap after Total Sacrectomy in Recurrent Sacral Chordoma - A Case Report -

박상민 , 정종훈 , Lee, Choon Ki and 2 other persons | 2016, 23(2) | pp.114~120 | number of Cited : 0

Extensive Intradural Epidermoid Cysts with Cauda Equina Syndrome in the Lumbosacral Spine - Case Report -

TAEKEUN AHN , Dongeun Shin , 권영우 and 1 other persons | 2016, 23(2) | pp.121~126 | number of Cited : 0

Huge Intradural Lumbar Disc Herniation Mimicking an Intradural Spinal Tumor - A Case Report -

Chung-Shik Shin , Byeong-Yeol Choi , Kyung-Tae Kim | 2016, 23(2) | pp.127~130 | number of Cited : 1

The Role of the Pelvis in Sagittal Alignment of Lumbar Degenerative Disease Patients

김용찬 , Ki-Han You , 장철영 and 6 other persons | 2016, 23(2) | pp.131~138 | number of Cited : 0

KJCKorea
Journal Central

Journal of Korean Society of Spine Surgery 2023 KCI Impact Factor : 0.03

2016, Vol.23, No.2