KJCKorea
Journal Central

@article{ART001237260},
author={김동준},
title={Autogenous Bone Graft and Bone Substitutes},
journal={Journal of Korean Society of Spine Surgery},
issn={2093-4378},
year={2008},
volume={15},
number={1},
pages={54-65}

TY - JOUR
AU - 김동준
TI - Autogenous Bone Graft and Bone Substitutes
JO - Journal of Korean Society of Spine Surgery
PY - 2008
VL - 15
IS - 1
PB - Korean Society Of Spine Surgery
SP - 54
EP - 65
SN - 2093-4378
AB - Study Design:Reviews were conducted. Objectives:This article is a review of the properties of the various bone grafting materials currently available and includes dis-cussion of their efficacy in clinical practice. Summary ofBackground Data:Bone grafting is frequently performed in spinal surgery to achieve fusion. Autograft is the goldstandard bone graft material. However, due to limitations of supply and morbidity associated with the harvest of autograft,alternatives are being considered. Methods:The available literature was reviewed. Results:Synthetic bone graft substitutes consist of hydroxyapatite, tricalcium phosphate, calcium sulfate, or a combination ofthese minerals. All synthetic porous substitutes share numerous advantages over autografts and allografts including theirunlimited supply, easy sterilization, and easy storage. However, they do confer some disadvantages such as brittle handlingproperties, variable rates of resorption, and poor performance in some clinical conditions. Recent attention has been focused onosteoinductive materials such as demineralized bone matrix, recombinant bone morphogenetic proteins, and blood product con-centrates. The primary categories of substitute include bone growth factors. Clinical trials are under way, and pre-clinical stud-ies have reported promising results for generating bone. Conclusions:Despite tremendous efforts toward developing autograft alternatives, a single ideal bone graft substitute has notbeen developed. The number of clinical studies and direct-comparison studies between these products is limited. The surgeonshould understand the properties of each bone graft substitute, to facilitate appropriate selection in each specific clinical situa-tion.
KW - Bone graft;Bone substitutes
DO -
UR -
ER -

김동준. (2008). Autogenous Bone Graft and Bone Substitutes. Journal of Korean Society of Spine Surgery, 15(1), 54-65.

김동준. 2008, "Autogenous Bone Graft and Bone Substitutes", Journal of Korean Society of Spine Surgery, vol.15, no.1 pp.54-65.

김동준 "Autogenous Bone Graft and Bone Substitutes" Journal of Korean Society of Spine Surgery 15.1 pp.54-65 (2008) : 54.

김동준. Autogenous Bone Graft and Bone Substitutes. 2008; 15(1), 54-65.

김동준. "Autogenous Bone Graft and Bone Substitutes" Journal of Korean Society of Spine Surgery 15, no.1 (2008) : 54-65.

김동준. Autogenous Bone Graft and Bone Substitutes. Journal of Korean Society of Spine Surgery, 15(1), 54-65.

김동준. Autogenous Bone Graft and Bone Substitutes. Journal of Korean Society of Spine Surgery. 2008; 15(1) 54-65.

김동준. Autogenous Bone Graft and Bone Substitutes. 2008; 15(1), 54-65.

김동준. "Autogenous Bone Graft and Bone Substitutes" Journal of Korean Society of Spine Surgery 15, no.1 (2008) : 54-65.