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Gelfoam Granuloma Formation and Myelopathy after Posterior Decompression in Thoracic Spine - A Case Report -

  • Journal of Korean Society of Spine Surgery
  • Abbr : J Kor Spine Sur
  • 2011, 18(4), pp.268-272
  • Publisher : Korean Society Of Spine Surgery
  • Research Area : Medicine and Pharmacy > Orthopedic Surgery

이규열 1 강진헌 1 김효종 1

1동아대학교

Accredited

ABSTRACT

Study design: A case report. Objectives: To document that Gelfoam®(Pharmacia & Upjohn, Kalamazoo, MI) contributes to granuloma formation and spinal cord irritation by immune response. Summary of Literature Review: The Gelfoam® or microfibrillar collagen applied during various operation for hemostasis. Some complications of Gelfoam®, such as mechanical cord compression, postoperative swelling and mass effect in closed cavity have been reported. Materials and Methods: The patient was underwent posterior decompression and instrumented posterolateral fusion under the diagnosis of the ossification of ligamentum flavum at T10-11 and T11-12. In operation, Gelfoam® was used at epidural space. She complained of sensory deterioration and muscle weakness around lower extremities after 10days postoperatively. A second operation was performed. Results: Postoperatively, the patient immediately improved motor grade except spasticity. She is under observation. Conclusion: Gelfoam® at epidural space after posterior decompression can result hyperactive immune reaction and irritate spinal cord.

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