Biphasic Calcium Phosphate and Local Autobone Mixed Graft in Lumbar Posterolateral Fusion (요추부 후측방 유합술시 이상인산칼슘 및 국소 자가골 혼합 이식술)

Jung-Wook Huh (허정욱); Young-Chul Ko (고영철); Chul-Young Jung (정철용); Il-Soo Eun (은일수); Man-Jun Park (박만준); Min-Woo Kim (김민우); 황금민; Sook-Hyun Park (박숙현)

Biphasic Calcium Phosphate and Local Autobone Mixed Graft in Lumbar Posterolateral Fusion

Journal of Korean Society of Spine Surgery
Abbr : J Kor Spine Sur
2014, 21(3), pp.103-108
Publisher : Korean Society Of Spine Surgery
Research Area : Medicine and Pharmacy > Orthopedic Surgery

Jung-Wook Huh ¹, Young-Chul Ko ¹, Chul-Young Jung ¹, Il-Soo Eun ¹, Man-Jun Park ¹, Min-Woo Kim ¹, 황금민 ¹, Sook-Hyun Park ¹

¹부산의료원 정형외과

Accredited

ABSTRACT

Study Design: Retroprospective study. Objectives: To evaluate the efficacy of biphasic calcium phosphate and local autobone mixed graft in cases of spinal stenosis andspondylolisthesis in posterolateral fusion by examining radiologic union rates and clinical outcomes. Summary of Literature Review: It can be a practical alternative to the use of tricalcium phosphate in hydroxyapatite as a graft aidsince using hydroxyapatite mixture in lumbar spine fusion has been reported to lead to a high rate of bone union. Materials and Methods: From July 2011 to February 2013, we followed up 107 patients who had lumbar posterolateral fusion usingbiphasic calcium phosphate composed of HA/TCP (60:40) and local autobone mixed graft. Of these patients, 64 had spinal stenosis and43 had spondylolisthesis. The bone fusion rate was determined using Lenke’s criteria and clinical outcomes were evaluated using Kim’smethod. Results: In spinal stenosis, bone union was presented in 53 patients (of 64; 82.8%) and in spondylolisthesis, 35 patients (of 43;81.4%). In spinal stenosis, the clinical outcomes resulted in 20 excellent, 34 good, 9 fair and 1 poor. (84.4%, excellent or good) Inspondylolisthesis, the clinical outcomes resulted in 10 excellent, 25 good, 7 fair and 1 poor. (81.4%, excellent or good)Conclusion: Posterolateral fusion using biphasic calcium phosphate and local autobone mixed graft showed high rates of bone unionand acceptable clinical outcomes, and is considered a satisfactory bone graft aid. Key Words: Spinal stenosis, Spondylolisthesis, Biphasic calcium phosphate, Posterolateral fusion

KEYWORDS

Spinal stenosis, Spondylolisthesis, Biphasic calcium phosphate, Posterolateral fusion

Citation status

* References for papers published after 2023 are currently being built.

[journal] Korovessis P / 2005 / Correlative radiological, self-assessment and clinical analysis if evolution in instrumented dorsal and lateral fusion for degenerative lumbar spine disease. Autograft versus coralline hydroxyapatite / Eur Spine J 14 : 630~638

[journal] Thalgott JS / 2001 / Instrumented posterolateral lumbar fusion using coralline hydroxyapatite with or without demineralized bone matrix, as an adjunct to autologous bone / Spine(Phila Pa 1976) 1 : 131~137

[journal] Arrington ED / 1996 / complications of iliac crest bone graft harvesting / Clin Orthop Relat Res 329 : 300~309

[journal] Banwart JC / 1995 / Iliac crest bone graft harvesting donor site morbidity. A statistical evaluation / Spine(Phila Pa 1976) 20 : 1055~1060

[journal] Younger EX / 1989 / Morbidity at bone graft donor sites / J Orthop Trauma 3 : 192~195

[journal] Kurz LT / 1989 / Harvesting autogenous iliac bone graft. A review of complication and techniques / Spine(Phila Pa 1976) 14 : 1324~1331

[journal] Finkemeier CG / 2002 / Bone-grafting and bone-graft substitutes / J Bone Joint Surg Am 84 : 454~464

[journal] Bucholz RW / 1989 / Interporous hydroxyapatite as a bone graft substitutes in tibial plateau fractures / Clin Orthop Relat Res 240 : 53~62

[journal] Boden SD / 1999 / The use of coralline hydroxyapatite with bone marrow, autogenous bone graft, or osteoinductive bone protein extract for posterolateral lumbar spine fusion / Spine(Phila Pa 1976) 24 : 320~327

[journal] Thalgott JS / 1999 / Anterior interbody fusion of the cervical spine with coralline hydroxyapatite / Spine(Phila Pa 1976) 24 : 1295~1299

[journal] Thalgott JS / 1997 / The use of coralline hydroxyapatite for interbody spinal fusions / Spine State Art Reviews 11 : 325~339

[journal] Lenke LG / 1992 / Contrel-Dubousset instrumentation for adolescent idiopathic scoliosis / J Bone Joint Surg Am 74 : 1056~1067

[journal] Kim NH / 1998 / Usefulness of posterolateral fusion of lumbar spine with allograft bone(tuboplast) / J Korean Soc Spine Surg 5 : 198~204

[journal] An HS / 1995 / Prospective comparison of autograft vs. allograft for adult posterolateral lumbar spine fusion: differences among freeze-dried, frozen and mixed grafts / J Spinal Disord 8 : 131~135

[journal] Ehrler DM / 2000 / The use of allograft bone in lumbar spine surgery / Clin Orthop Relat Res 371 : 38~45

[journal] Beaman FD / 2006 / Bone graft material and synthetic substitutes / Radiol Clin North Am 44 : 451~461

[journal] Burchardt H / 1983 / The biology of bone graft repair / Clin Orthop Relat Res 174 : 28~42

[journal] Gauthier O / 1998 / Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth / Biomaterials 19 : 133~139

[journal] 정웅서 / 2008 / Comparison of the Effect of Hydroxyapatite and Allogenous Bone as an Adjunct to Autogenous Iliac Bone Grafting in Posterolateral Spinal Fusion / 대한정형외과학회지 / 대한정형외과학회 43(3) : 347~352

[journal] Walsh WR / 2000 / Mechanical and histologic evaluation of Collagraft in an ovine lumbar fusion model / Clin Orthop Relat Res 375 : 258~266

[journal] Murat C / 2008 / The results of b-tricalcium phosphate coated hydroxyapatite(b-TCP/HA)grafts for interbody fusion after anterior cervical discectomy / J Spinal Disord Tech 21 : 436~441

[journal] Park KC / 2010 / Comparative analysis of graft extender in lumbar spinal fusion / J Korean Musculoskelet Transplant Soc 10 : 43~49

[journal] Ricciardi JE / 1995 / Transpedicular fixation for the treatment of isthmic spondylolisthesis in adults / Spine(Phila Pa 1976) 20 : 1917~1922

[journal] Shin BJ / 1996 / Surgical results of isthmic spondylolisthesis – Comparison of posterolateral fusion vs PLIF / J Korean Soc Spine Surg 3 : 61~68

[journal] Yang JY / 2006 / The effect of β-tricalcium phosphate in lumbar posterolateral fusion surgery –A prospective study- / J Korean Musculoskelet Transplant Soc 6 : 13~18

[journal] Ahn JS / 1999 / Relationship between union grafted autologous bone and clinical results of operative treatment of degenerative spondylolisthesis by posterolateral fusion / J Korean Orthop Assoc 34 : 95~101

[journal] Aprin H / 1982 / Spine fusion in patient with spinal muscular atrophy / J Bone Joint Surg 64 : 1179~1187

KJCKorea
Journal Central

Journal of Korean Society of Spine Surgery 2023 KCI Impact Factor : 0.03