Conservative Treatment of Osteoporotic Spinal Fractures (골다공증성 척추골절의 보존적 치료)

Lee, Jae Hyup (이재협); 김원철; Lee， Jiho (이지호)

Conservative Treatment of Osteoporotic Spinal Fractures

Journal of Korean Society of Spine Surgery
Abbr : J Kor Spine Sur
2015, 22(4), pp.186-191
Publisher : Korean Society Of Spine Surgery
Research Area : Medicine and Pharmacy > Orthopedic Surgery

Lee, Jae Hyup ¹, 김원철 ¹, Lee， Jiho ¹

¹서울대학교

Accredited

ABSTRACT

Study Design: Literature review. Objectives: To present updated information on the conservative treatment of osteoporotic spinal fractures (OSFs). Summary of Literature Review: The treatments of osteoporotic spinal fractures are bed rest, pain medication, bracing, exercise and rehabilitation, and osteoporosis medication. However, there is disagreement about the outcomes of these treatments. Materials and Methods: Review of the relevant literature. Results: In the case of osteoporotic spinal fractures, analgesic administration, bracing, physical therapy, and exercise should be conducted. In order to prevent secondary fractures, bisphosphonates, selective estrogen receptor modulators, strontium ranelate, or parathyroid hormone, which has proven efficacy with respect to the prevention of secondary fractures, should be prescribed. Conclusions: We should actively prevent the occurrence of secondary fractures with fracture healing by implementing a proven effective treatment for osteoporotic spinal fractures.

KEYWORDS

Osteoporosis, Spinal fractures, Treatment, Conservative

Citation status

* References for papers published after 2023 are currently being built.

[journal] Robin H / 2001 / A new system for grading recommendations in evidence based guidelines / BMJ 323 : 334~336

[journal] Gerdhem P. / 2013 / Osteoporosis and fragility fractures: Vertebral fractures / Best Pract Res Clin Rheumatol 7 : 743~755

[journal] Cherubiono P / 2012 / The management of chronic pain in important patient subgroups / Clin Drug Investig 32 : 35~44

[journal] Cherasse A / 2004 / Tolerability of opioids in patients with acute pain due to nonmalignant musculoskeletal disease. A hospital-based observational study / Joint Bone Spine 71 : 572~576

[journal] Longo UG / 2012 / Osteoporotic vertebral fractures : current concepts of conservative care / Br Med bull 102 : 171~189

[journal] van Tulder MW / 2003 / Muscle relaxants for non-specific low back pain / Cochrane Database Syst Rev 2 : CD004252~

[journal] Cauley JA / 2011 / Once-yearly zoledronic acid and days of disability, bed rest, and back pain:randomized, controlled HORIZON Pivotal Fracture Trial / J Bone Miner Res 26 : 984~992

[journal] Rovetta G / 2001 / One-month follow-up of patients treated by intravenous clodronate for acute pain induced by osteoporotic vertebral fracture / Drugs Exp Clin Res 27 : 77~81

[journal] Rovetta G / 2000 / Intravenous clodronate for acute pain induced by osteoporotic vertebral fracture / Drugs Exp Clin Res 26 : 25~30

[journal] Armingeat T / 2006 / Intravenous pamidronate for pain relief in recent osteoporotic vertebral compression fracture: a randomized double-blind controlled study / Osteoporos Int 17 : 1659~1665

[journal] Black DM / 1996 / Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group / Lancet 348 : 1535~1541

[journal] Wells GA / 2008 / Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women / Cochrane Database Syst Rev 1 : CD001155~

[journal] Reginster J / 2000 / Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) Study Group / Osteoporos Int 11 : 83~91

[journal] Wells G / 2008 / Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women / Cochrane Database Syst Rev 1 : CD004523~

[journal] Delmas PD / 2004 / Daily and intermittent oral ibandronate normalize bone turnover and provide significant reduction in vertebral fracture risk: results from the BONE study / Osteoporos Int 15 : 792~798

[journal] Chesnut CH 3rd / 2004 / Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis / J Bone Miner Res 19 : 1241~1249

[journal] Ettinger B / 1999 / Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators / JAMA 282 : 637~645

[journal] Silverman SL / 2008 / Efficacy of bazedoxifene in reducing new vertebral fracture risk in postmenopausal women with osteoporosis: results from a 3-year, randomized, placebo-, and active-controlled clinical trial / J Bone Miner Res 23 : 1923~1934

[journal] Meunier PJ / 2004 / The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis / N Engl J Med 350 : 459~468

[journal] Chesnut CH 3rd / 2000 / A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group / Am J Med 109 : 267~276

[journal] Neer RM / 2001 / Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis / N Engl J Med 344 : 1434~1441

[journal] Cheng MH / 2012 / Osteoporosis treatment in postmenopausal women with pre-existing fracture / Taiwan J Obstet Gynecol 51 : 153~166

[journal] Eastell R / 2009 / Sequential treatment of severe postmenopausal osteoporosis after teriparatide:final results of the randomized, controlled European Study of Forsteo (EUROFORS) / J Bone Miner Res 24 : 726~736

[journal] Kim HJ / 2014 / Comparative study of the treatment outcomes of osteoporotic compression fractures without neurologic injury using a rigid brace, a soft brace, and no brace: a prospective randomized controlled noninferiority trial / J Bone Joint Surg Am 96 : 1959~1966

[journal] Rzewuska M / 2015 / The efficacy of conservative treatment of osteoporotic compression fractures on acute pain relief: a systematic review with metaanalysis / Eur Spine J 24 : 702~714

[journal] Howe TE / 2011 / Exercise for improving balance in older people / Cochrane Database Syst Rev 11 : CD000333~

[journal] Gillespie LD / 2012 / Interventions for preventing falls in older people living in the community / Cochrane Database Syst Rev 9 : CD007146~

[journal] Giangregorio LM / 2013 / Exercise for improving outcomes after osteoporotic vertebral fracture / Cochrane Database Syst Rev 1 : CD008618~

[journal] Bergland A / 2011 / Effect of exercise on mobility, balance, and health-related quality of life in osteoporotic women with a history of vertebral fracture: a randomized, controlled trial / Osteoporos Int 22 : 1863~1871

[journal] Gold DT / 2004 / Group treatment improves trunk strength and psychological status in older women with vertebral fractures: results of a randomized, clinical trial / J Am Geriatr Soc 52 : 1471~1478

[journal] Papaioannou A / 2003 / Efficacy of home-based exercise for improving quality of life among elderly women with symptomatic osteoporosis-related vertebral fractures / Osteoporos Int 14 : 677~682

[journal] Bennell KL / 2010 / Effects of an exercise and manual therapy program on physical impairments, function and quality-of-life in people with osteoporotic vertebral fracture: a randomised, single-blind controlled pilot trial / BMC Musculoskelet Disord 11 : 36~

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