Clinical Efficacy and Safety of Radiofrequency Ablation Therapy with Cement Augmentation for a Metastatic Spine Tumor (전이성 척추 종양 환자에서 고주파 열 용해술 후 척추 시멘트 충전술의 임상적 효용성과 안정성)

Kim chang su (김창수); Young-Ho Kwon (권영호); Chung So Hak (정소학); Samuel Baek (백사무엘)

Clinical Efficacy and Safety of Radiofrequency Ablation Therapy with Cement Augmentation for a Metastatic Spine Tumor

Journal of Korean Society of Spine Surgery
Abbr : J Kor Spine Sur
2016, 23(4), pp.207-215
Publisher : Korean Society Of Spine Surgery
Research Area : Medicine and Pharmacy > Orthopedic Surgery

Kim chang su ¹, Young-Ho Kwon ¹, Chung So Hak ¹, Samuel Baek ²

¹고신대학교
²고신대학교 복음병원 정형외과학교실

Accredited

ABSTRACT

Study Design: Retrospective study. Objectives: To evaluate the clinical efficacy and safety of radiofrequency (RF) ablation therapy followed by a bone cement augmentation procedure in treating and managing pain among metastatic spine tumor patients. Summary of Literature Review: As a metastatic spine tumor is unresectable, this procedure was performed. Results showed an increase in the necrosis rate, and a decrease in local recurrence and secondary vertebral stability. Materials and Methods: From March 2007 to April 2016, 26 patients who were treated with RF ablation with a bone cement augmentation procedure and the same number of patients treated with radiotherapy for metastatic spine lesions were included in this study. Pain relief and functional quality of life were evaluated using a visual analogue scale (VAS) and Roland Morris Questionnaire (RMQ). Results: VAS scores preoperatively and at 1, 4, and 12 weeks follow-up were 7.45, 3.01, 3.78, and 2.97 in the procedure group, and 7.04, 6.65, 5.87, and 3.03 in the radiotherapy group. The procedure group had significantly better average outcomes than the radiotherapy group for pain relief at 4 weeks but showed no difference at 12 weeks. The RMQ score improved from 13.92 to 7.21 in the procedure group, and from 15.33 to 9.75 in the radiotherapy group. Two patients who had a metastatic tumor near the vertebral body posterior cortex showed cement leakage into the disc space, that is, intraforaminal and intracanal space; therefore, operations were performed (7.69% nerve injury). Conclusions: RF ablation therapy with cement augmentation in treatment of metastatic spine tumor shows effectiveness in early pain relief and brings immediate vertebral stability, helping patients return to normal life. However, it carries a risk of nerve injury due to cement leakage.

KEYWORDS

Radiofrequency ablation, Cement augmentation, Spinal metastases, Pain relief, Cement leakage

Citation status

* References for papers published after 2023 are currently being built.

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