A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part I )- Bamboo Extract - (아토피성 피부염병변에 치료효과가 있는 천연염료 연구(1)-대나무 추출물-)

Lee, Jung-soon (이정순); Go Eun Jeong (정고은)

A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part I )- Bamboo Extract -

Textile Coloration and Finishing
Abbr : Text. Color. and Finish.
2012, 24(3), pp.189-195
Publisher : The Korean Society Of Dyers And Finishers
Research Area : Engineering > Fiber Engineering > Dyeing Engineering

Lee, Jung-soon ¹, Go Eun Jeong ²

¹충남대학교
²한국섬유소재연구소

Accredited

ABSTRACT

The purpose of this study was to investigate the possibility of bamboo extract as natural dye having the effect on atopic dermatitis(AD). To investigate the effect of bamboo extract on AD in vivo, we applied bamboo extract to the AD-like skin lesion the backs of atopic of NC/Nga mice, an animal model of AD. NC/Nga mice were challenged with DNCB(2.4-Dinitrochlorbenzene) to develope AD-like skin lesions. The efficacy of bamboo extract in the NC/Nga mice was evaluated by measurement of the skin lesion severity(NC mouse score), the serum IgE level, epidermal thickness changes, and mast cell number. Bamboo extracts improved skin lesions in NC/Nga mice. The serum IgE levels were decreased after treatment with bamboo extract. Histological examinations revealed a decrease in epidermal thickness and mast cell number after treatment with bamboo extract. To conclude, the topical application of bamboo extract suppressed the progression of AD-like skin lesions.

KEYWORDS

bamboo extract, natural dye, atopic dermatitis, NC/Nga mice, DNCB

Citation status

* References for papers published after 2023 are currently being built.

This paper was written with support from the National Research Foundation of Korea.

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