@article{ART001697972},
author={Lee, Jung-soon and Hyo Jung Woo},
title={A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract},
journal={Textile Coloration and Finishing },
issn={1229-0033},
year={2012},
volume={24},
number={3},
pages={196-203}
TY - JOUR
AU - Lee, Jung-soon
AU - Hyo Jung Woo
TI - A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract
JO - Textile Coloration and Finishing
PY - 2012
VL - 24
IS - 3
PB - The Korean Society Of Dyers And Finishers
SP - 196
EP - 203
SN - 1229-0033
AB - The purpose of this study was to investigate usefulness of the pine needles extract on Atopic Dermatitis(AD)-like skin lesions. To investigate the effect of pine needles extract in vivo, atopic dermatitis (NC/Nga) mice using DNCB (2.4-Dinitrochlorbenzene) was used. NC/Nga mice were challenged with DNCB during 2 weeks to develope AD-like skin lesion.
After that, pine needles extract was applied to AD-like skin lesion on the backs of the NC/Nga mice during 3 weeks. The efficacy of pine needles extract in the NC/Nga mice was evaluated by measurement of the skin lesion severity(NC mouse score), the serum IgE level, epidermal thickness changes, and mast cell number. Blood was collected from the retro-orbital area and the level of IgE in the blood was measured. The epidermal thickness and mast cell number were observed by microscopic method after H&E stain. The serum IgE levels were decreased after treatment with pine needles extract. The epidermal thickness and mast cell number were decreased after treatment with pine needles extract. To conclude, the topical application of pine needles extract suppressed the progression of AD-like skin lesion.
KW - pine needles extract;natural dye;atopic dermatitis;NC/Nga mice;DNCB
DO -
UR -
ER -
Lee, Jung-soon and Hyo Jung Woo. (2012). A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract. Textile Coloration and Finishing , 24(3), 196-203.
Lee, Jung-soon and Hyo Jung Woo. 2012, "A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract", Textile Coloration and Finishing , vol.24, no.3 pp.196-203.
Lee, Jung-soon, Hyo Jung Woo "A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract" Textile Coloration and Finishing 24.3 pp.196-203 (2012) : 196.
Lee, Jung-soon, Hyo Jung Woo. A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract. 2012; 24(3), 196-203.
Lee, Jung-soon and Hyo Jung Woo. "A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract" Textile Coloration and Finishing 24, no.3 (2012) : 196-203.
Lee, Jung-soon; Hyo Jung Woo. A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract. Textile Coloration and Finishing , 24(3), 196-203.
Lee, Jung-soon; Hyo Jung Woo. A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract. Textile Coloration and Finishing . 2012; 24(3) 196-203.
Lee, Jung-soon, Hyo Jung Woo. A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract. 2012; 24(3), 196-203.
Lee, Jung-soon and Hyo Jung Woo. "A Study on Natural Dye Having the Effects on the Atopic Dermatitis (Part )- Pine Needles Extract" Textile Coloration and Finishing 24, no.3 (2012) : 196-203.