Effect of Low Frequency Electrical Stimulation on VEGF Expression of Suspension Induced Atrophic Muscle (뒷다리 현수 유도 위축근에 대한 저빈도 전기자극의 VEGF 발현에 미치는 영향 )

강종호; Han jong man (한종만)

Effect of Low Frequency Electrical Stimulation on VEGF Expression of Suspension Induced Atrophic Muscle

Journal of the Korean Society of Physical Medicine
Abbr : J Korean Soc Phys Med
2010, 5(2), pp.273-280
Publisher : The Korean Society of Physical Medicine
Research Area : Medicine and Pharmacy > Physical Therapy > Other physical therapy

강종호 ¹, Han jong man ²

¹남부대학교
²전남과학대학

Candidate

ABSTRACT

Purpose：The purpose of this experiment was to evaluate the pre-application effect of low frequency electrical stimulation(LFES) on VEGF expression of atrophic muscle and to determine the optimal pre-application period of LFES for prevent muscle atropy Methods：Twenty-five adult sprague-dawley rats were randomly assigned to weight bearing group, hindlimb suspension for 14 days group, hindlimb suspension with pre-application of LFES for 14 days group, hindlimb suspension with pre-application of LFES for 11 dsys group and, hindlimb suspension with pre-application LFES for 7 dsys group. 16Hz of Biphasic pulse current was applied to gastrocnemius for 15min per days. Results：VEGF were decreased expression in HSG groups, whereas VEGF were significantly increased in HS+ES14G, HS+ES11G, HS+ES7G groups Conclusion：LFES during the hindlimb suspension showed a positive effect in VEGF induction and early application is strongly encourage VEGF induction. This indicated that pre-application of LFES could prevent muscle atrophy.

KEYWORDS

Muscle atrophy, Low frequency electrical stimulation, Vascular endothelial growth factor

Citation status

* References for papers published after 2023 are currently being built.

[thesis] 남기원 / 2003 / 신경근전기자극과 수중운동이 흰쥐 위축근 신경근연접부의 연접재형성에 미치는 영향 / 박사 / 대구대학교

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