Influence of Joint Mobilization on Formalin Induced Pain Prevention of Rats (관절가동술이 흰쥐의 포르말린 유도 통증 예방에 미치는 영향)

강종호; Kim EunKyung (김은경); 노효련

Influence of Joint Mobilization on Formalin Induced Pain Prevention of Rats

Journal of the Korean Society of Physical Medicine
Abbr : J Korean Soc Phys Med
2011, 6(2), pp.207-213
Publisher : The Korean Society of Physical Medicine
Research Area : Medicine and Pharmacy > Physical Therapy > Other physical therapy

강종호 ¹, Kim EunKyung ², 노효련 ³

¹남부대학교
²서남대학교
³강원대학교

Candidate

ABSTRACT

Purpose：The purpose of this study was to determine the preventive effect of joint mobilization on biphasic pain response induced formalin test. Methods：Sprague-dawley rats(n=30) were ramdomly divided into the control group without intervention, sham control group with application of hand contact without mobilization, joint mobilization group with application of hand contact with mobilization. Joint mobilization of knee procedure involved an grade III extension mobilization basically with anterior-posterior gliding of the tibia on the femur. Formalin injection caused biphasic pain response which is lated for 60 minute. The first phase result from primary afferent sensory fiber, wheareas the second phase has been proposed to central sensitization in the central nervous system. Behavioral analysis was performed by digital camera after 5% formalin subcutaneous injection into the dorsal foot. Results：Pain response of joint mobilization group show significant lower than control gorup and sham control group. Conclusion：This result suggest that pre-application of joint mobilization may be effective intervention to prevent the formalin induced pain.

KEYWORDS

Joint mobilization, Preemptive analgesics, Formalin test

Citation status

* References for papers published after 2023 are currently being built.

[journal] 이영화 / 2008 / 척추후관절가동술이 만성요통환자의 통증과 요부안정성에 미치는 영향 / 대한물리의학회지 3(3) : 203~213

[journal] Abbott FV / 1995 / The formalin test: scoring properties of the first and second phases of the pain response in rats / Pain 60(1) : 91~102

[journal] Aquino RL / 2009 / Applying Joint Mobilization at Different Cervical Vertebral Levels does not Influence Immediate Pain Reduction in Patients with Chronic Neck Pain: A Randomized Clinical Trial / J Man Manip Ther 17(2) : 95~100

[journal] Capone F / 2004 / Aloisi AM. Refinement of pain evaluation techniques / The formalin test. Ann Ist Super Sanita 40(2) : 223~229

[journal] Collins N / 2004 / The initial effects of a Mulligan's mobilization with movement technique on dorsiflexion and pain in subacute ankle sprains / Man Ther 9(2) : 77~82

[journal] Esther S / 1999 / Decrease in quadriceps inhibition after sacroiliac joint manipulation in patients with anterior knee pain / J Mnipulative Physiol Ther 22(3) : 149~153

[journal] Fernández-de-Las-Peñas C / 2008 / Changes in Pressure Pain Thresholds Over C5-C6 Zygapophyseal Joint After a Cervicothoracic Junction Manipulation in Healthy Subjects / J of Manipulative Physiol Ther 31(5) : 332~337

[journal] Ferreira ML / 2002 / Does spinal manipulative therapy help people with chronic low back pain / Aust J Physiother 48(4) : 277~284

[journal] Grape S / 2007 / Do we need preemptive analgesia for the treatment of postoperative pain? Best Pract / Res Clin Anaesthesiol 21(1) : 51~63

[journal] Green T / 2001 / Randomized controlled trial of a passive accessory joint mobilization on acute ankle inversion sprains / Phys Ther 81(4) : 984~994

[journal] Kelly DJ / 2001 / Preemptive analgesia II: recent advances and current trends / Can J Anaesth 48(11) : 1091~1101

[journal] Kelly DJ / 2001 / Preemptive analgesia I: physiological pathways and pharmacological modalities / Can J Anaesth 48(10) : 1000~1010

[book] Kisner C / 2002 / Therapeutic Exercise: Foundations and Techniques. 4th edition / F.A. Davis Co

[book] Maitland GD / 1986 / Vertebral Manipulation 5th ed / Butterworths

[journal] McNair PJ / 2007 / Acute neck pain: cervical spine range of motion and position sense prior to and after joint mobilization / Man Ther 12(4) : 390~394

[journal] Moss P / 2007 / The initial effects of knee joint mobilization on osteoarthritic hyperalgesia / Man Ther 12(2) : 109~118

[journal] Okuda K / 2001 / Characterization of nociceptive responses and spinal releases of nitric oxide metabolites and glutamate evoked by different concentrations of formalin in rats / Pain 92(1) : 107~115

[book] Sandler AN / 1992 / Anesthsiology Clinics of North America: Current concepts in acute pain control / WB Saunders

[journal] Savegnago L / 2008 / Mechanisms involved in the antinociceptive effect caused by diphenyl diselenide in the formalin test / J Pharm Pharmacol 60(12) : 1679~1686

[journal] Sevostianova N / 2003 / Effects of morphine on formalin-induced nociception in rats / Eur J Pharmacol 462(1) : 109~113

[journal] Sherman C / 2009 / Rehabilitation Therapy for Elbow Disorders in Dogs / Veterinary Surgery 38(2) : 301~307

[journal] Shields SD / 2010 / Pain behavior in the formalin test persists after ablation of the great majority of C-fiber nociceptors / Pain 151(2) : 422~429

[journal] Sluka KA / 2006 / Joint mobilization reduces hyperalgesia associated with chronic muscle and joint inflammation in rats / J Pain 7(8) : 602~607

[journal] Song XJ / 2006 / Spinal manipulation reduces pain and hyperalgesia after lumbar intervertebral foramen inflammation in the rat / J Manipulative Physiol Ther 29(1) : 5~13

[journal] Sufka KJ / 1998 / Scoring the mouse formalin test: validation study / Display Settings 2(4) : 351~358

[journal] Sun OS / 1995 / Pre-emptive infiltration of lidocaine reduces formalin pain behavior in rat / Korean J Anesthesiol 29(6) : 790~797

[journal] Tjolsen A / 1992 / The formalin test: An evaluation of the method / Pain 51(1) : 5~17

[journal] Vaccarino AL / 1994 / Descending modulation of central neural plasticity in the formalin pain test / Brain Res 666(1) : 104~108

[journal] Vicenzino B / 1996 / The initial effects of a cervical spine manipulative physiotherapy treatment on the pain and dysfunction of lateral epicondylalgia / Pain 68(1) : 69~74

[journal] Watson GS / 1997 / Optimal scoring strategies and weights for the formalin test in rats / Pain 70(1) : 53~58

KJCKorea
Journal Central

Journal of the Korean Society of Physical Medicine 2023 KCI Impact Factor : 0.45