Effects of Individualized Intensive Physical Therapy for a Child with MECP2 Duplication Syndrome: A Case Study

Yonsei Child Development Center (김창호)

Effects of Individualized Intensive Physical Therapy for a Child with MECP2 Duplication Syndrome: A Case Study

Journal of the Korean Society of Physical Medicine
Abbr : J Korean Soc Phys Med
2023, 18(4), pp.29-35
Publisher : The Korean Society of Physical Medicine
Research Area : Medicine and Pharmacy > Physical Therapy > Other physical therapy
Received : September 20, 2023
Accepted : October 31, 2023
Published : November 30, 2023

Yonsei Child Development Center ¹

¹연세아동발달센터

Accredited

ABSTRACT

PURPOSE: High-intensity physical therapy may help improve some gross motor developmental delays through an increased treatment frequency. This study describes an increase in physical therapy frequency and intensity over an eight-week time frame for a child with a rare genetic neurodevelopmental disorder. METHODS: A single-subject research was performed. The subject was a nine-year-old boy with MECP2 Duplication Syndrome. The outcome measure consisted of one time before and after the intervention. An intensive physical therapy program was applied to this subject. The treatments included reciprocal crawling, high kneeling, tailor sitting, weight-bearing and shifting training to facilitate ankle balance strategies and training to walk without assistance. RESULTS: After the eight-week follow-up, the child achieved a gradual improvement in the gross motor function measures, and the mother reported that the child frequently engaged in tailor sitting and independently walking. CONCLUSION: This case study highlights that intensive physical therapy improved the overall motor function of a child with MECP2 duplication syndrome.

KEYWORDS

Case reports, Genetic diseases, Physical therapy modalities

Citation status

* References for papers published after 2023 are currently being built.

[journal] Ramocki MB / 2010 / The M ECP2duplication syndrome / Am J Med Genet A 152A(5) : 1079~1088

[journal] Das SP / 2019 / Evidence-based approach to physical therapy in cerebral palsy / Indian J Orthop 53(1) : 20~34

[journal] Odman P / 2005 / Effectiveness of intensive training for children with cerebral palsy : A comparison between child and youth rehabilitation and conductive education / J Rehabil Med 37(4) : 263~270

[journal] Trahan J / 2002 / Intermittent intensive physiotherapy in children with cerebral palsy : a pilot study / Dev Med Child Neurol 44(4) : 233~239

[journal] World Medical Association / 2001 / World medical association declaration of helsinki. ethical principles for medical research involving human subjects / Bull World Health Organ 79(4) : 373~374

[journal] Law M / 2014 / Emerging therapy approaches : an emphasis on function / J Child Neurol 29(8) : 1101~1107

[journal] Alotaibi M / 2014 / The efficacy of GMFM-88 and GMFM-66 to detect changes in gross motor function in children with cerebral palsy(CP) : a literature review / Disabil Rehabil 36(8) : 617~627

[journal] 박은영 / 2010 / Comparison of Reliability and Validity Between GMFM-88 and GMFM-66 in Children With Cerebral Palsy / 한국전문물리치료학회지 / 한국전문물리치료학회 17(3) : 40~47

[journal] Husaini MA / 2010 / Normal motor milestone development for use to promote child care / Paediatr Indones 50(6) : 340~346

[journal] Bower E / 2001 / R andomized controlled trial of physiotherapy in 56 children with cerebral palsy followed for 18 months / Dev Med Child Neurol 43(1) : 4~15

[journal] Chao HT / 2012 / MeCP2 : only 100% will do / Nat Neurosci 15(2) : 176~177

[journal] Westcott SL / 1997 / Evaluation of postural stability in children : current theories and assessment tools / Phys Ther Rehabil 77(6) : 629~645

[journal] Menon A / 2009 / Strategies for rehabilitation professionals to move evidence-based knowledge into practice : a systematic review / J Rehabil Med 41(13) : 1024~1032

[journal] Straus SE / 2009 / Defining knowledge translation / CMAJ 181(3-4) : 165~168

[journal] Shamir M / 2012 / Intensive intermittent physical therapy in infants with cerebral palsy : a randomized controlled pilot study / Isr Med Assoc J 14(12) : 737~741

[journal] Tsorlakis N / 2004 / Effect of intensive neurodevelopmental treatment in gross motor function of children with cerebral palsy / Dev Med Child Neurol 46(11) : 740~745

[journal] Toovey RAM / 2022 / Task-specific training for bicycle-riding goals in ambulant children with cerebral palsy : a randomized controlled trial / Dev Med Child Neurol 64(2) : 243~252

[journal] Palisano RJ / 2007 / The case report, case study, and single subject design / Phys Occup Ther Pediatr 27(4) : 1~5

[journal] Rison RA / 2016 / When to write a neurology case report / J Med Case Rep 10 : 92~

KJCKorea
Journal Central

Journal of the Korean Society of Physical Medicine 2023 KCI Impact Factor : 0.45