@article{ART001700146},
author={장문희 and Jae-Song Choi and 최애련 and Taek-won Ahn},
title={Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2012},
volume={24},
number={3},
pages={80-92},
doi={10.7730/JSCM.2012.24.3.80}
TY - JOUR
AU - 장문희
AU - Jae-Song Choi
AU - 최애련
AU - Taek-won Ahn
TI - Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2012
VL - 24
IS - 3
PB - The Society of Sasang Constitution and Immune Medicine
SP - 80
EP - 92
SN - 1226-4075
AB - Objectives The purpose of this study is to investigate the effects of korean herbal bathing extracts composition 1 and composition 2 on Th2 cytokine production in MC/9 mast cells.
Methods The effects of composition 1, 2 was analyzed by ELISA and Real-time PCR in MC/9 mast cells. Levels of IL-5, IL-13 were measured using enzyme-linked immunosorbent assays(ELISA). mRNA levels of IL-4, IL-5, IL-6, IL-13 were analyzed with Real-time PCR.
Results Composition 1, 2 inhibited the IL-5, IL-13 production signifcantly(p<.001) in comparison to PI-control group at concentration of 100 ㎍/mL, 200 ㎍/mL. Composition 1, 2 inhibited the IL-4, IL-5, IL-13 mRNA expression signifcantly in comparison to PI-control group at concentration of 100 ㎍/mL, 200 ㎍/mL. Composition 1 inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of 200 ㎍/㎖. Composition 2 inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of 100 ㎍/mL, 200 ㎍/mL.
Conclusions These results indicate that composition 1, 2 has the effect of decreasing the Th2 cytokine production in the MC/9 mast cell.
KW - Korean Herbal Bathing Extracts Composition;Cytokine;MC/9 Mast Cell;Atopic Dermatitis.
DO - 10.7730/JSCM.2012.24.3.80
ER -
장문희, Jae-Song Choi, 최애련 and Taek-won Ahn. (2012). Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells. Journal of Sasang Constitution and Immune Medicine, 24(3), 80-92.
장문희, Jae-Song Choi, 최애련 and Taek-won Ahn. 2012, "Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells", Journal of Sasang Constitution and Immune Medicine, vol.24, no.3 pp.80-92. Available from: doi:10.7730/JSCM.2012.24.3.80
장문희, Jae-Song Choi, 최애련, Taek-won Ahn "Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells" Journal of Sasang Constitution and Immune Medicine 24.3 pp.80-92 (2012) : 80.
장문희, Jae-Song Choi, 최애련, Taek-won Ahn. Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells. 2012; 24(3), 80-92. Available from: doi:10.7730/JSCM.2012.24.3.80
장문희, Jae-Song Choi, 최애련 and Taek-won Ahn. "Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells" Journal of Sasang Constitution and Immune Medicine 24, no.3 (2012) : 80-92.doi: 10.7730/JSCM.2012.24.3.80
장문희; Jae-Song Choi; 최애련; Taek-won Ahn. Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells. Journal of Sasang Constitution and Immune Medicine, 24(3), 80-92. doi: 10.7730/JSCM.2012.24.3.80
장문희; Jae-Song Choi; 최애련; Taek-won Ahn. Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells. Journal of Sasang Constitution and Immune Medicine. 2012; 24(3) 80-92. doi: 10.7730/JSCM.2012.24.3.80
장문희, Jae-Song Choi, 최애련, Taek-won Ahn. Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells. 2012; 24(3), 80-92. Available from: doi:10.7730/JSCM.2012.24.3.80
장문희, Jae-Song Choi, 최애련 and Taek-won Ahn. "Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells" Journal of Sasang Constitution and Immune Medicine 24, no.3 (2012) : 80-92.doi: 10.7730/JSCM.2012.24.3.80
