@article{ART002241177},
author={고가연 and PARK JUNGHWAN and jinyoung kwak and Taek-won Ahn},
title={Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2017},
volume={29},
number={2},
pages={154-173},
doi={10.7730/JSCM.2017.29.2.154}
TY - JOUR
AU - 고가연
AU - PARK JUNGHWAN
AU - jinyoung kwak
AU - Taek-won Ahn
TI - Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2017
VL - 29
IS - 2
PB - The Society of Sasang Constitution and Immune Medicine
SP - 154
EP - 173
SN - 1226-4075
AB - Objectives This study was conducted to evaluate the effects of Yeoldahanso-tang on obesity in rats induced by high fat diet experimentally.
Methods The experiment was conducted with rats divided into 5 groups. Rats were evaluated for change of weight, hematologic and serum biochemical parameters.
Results Yeoldahanso-tang group showed significant reductions in FER, body weight, adipose tissue weight and size. The level of Creatinine, glucose, ALP, T-cholesterol, Triglyceride, LDL-cholesterol, Leptin and IGF-1 of Yeoldahanso-tang group was significantly lower than those in HFD-CTL group. The level of HDL-cholesterol, free fatty acid and Adiponectin in Yeoldahanso-tang group was significantly higher than those in HFD-CTL group. As compared with HFD-CTL group, AMPK-α1, UCP2 and adiponectin mRNA in liver of Yeoldahanso-tang group were significantly increased and AP2/FABP4, AMPK-α2 and PPAR-γ mRNA in liver of Yeoldahanso-tang group was significantly decreased.
Conclusion These results suggest that Yeoldahanso-tang has inhibitory effects on obesity in high fat diet induced obese mice.
KW - Yeoldahanso-tang;anti-obesity;High fat diet;anti-hyperlipidemia
DO - 10.7730/JSCM.2017.29.2.154
ER -
고가연, PARK JUNGHWAN, jinyoung kwak and Taek-won Ahn. (2017). Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice. Journal of Sasang Constitution and Immune Medicine, 29(2), 154-173.
고가연, PARK JUNGHWAN, jinyoung kwak and Taek-won Ahn. 2017, "Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice", Journal of Sasang Constitution and Immune Medicine, vol.29, no.2 pp.154-173. Available from: doi:10.7730/JSCM.2017.29.2.154
고가연, PARK JUNGHWAN, jinyoung kwak, Taek-won Ahn "Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice" Journal of Sasang Constitution and Immune Medicine 29.2 pp.154-173 (2017) : 154.
고가연, PARK JUNGHWAN, jinyoung kwak, Taek-won Ahn. Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice. 2017; 29(2), 154-173. Available from: doi:10.7730/JSCM.2017.29.2.154
고가연, PARK JUNGHWAN, jinyoung kwak and Taek-won Ahn. "Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice" Journal of Sasang Constitution and Immune Medicine 29, no.2 (2017) : 154-173.doi: 10.7730/JSCM.2017.29.2.154
고가연; PARK JUNGHWAN; jinyoung kwak; Taek-won Ahn. Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice. Journal of Sasang Constitution and Immune Medicine, 29(2), 154-173. doi: 10.7730/JSCM.2017.29.2.154
고가연; PARK JUNGHWAN; jinyoung kwak; Taek-won Ahn. Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice. Journal of Sasang Constitution and Immune Medicine. 2017; 29(2) 154-173. doi: 10.7730/JSCM.2017.29.2.154
고가연, PARK JUNGHWAN, jinyoung kwak, Taek-won Ahn. Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice. 2017; 29(2), 154-173. Available from: doi:10.7730/JSCM.2017.29.2.154
고가연, PARK JUNGHWAN, jinyoung kwak and Taek-won Ahn. "Anti-obesity Effect of Yeoldahanso-tang on Obesity Mice" Journal of Sasang Constitution and Immune Medicine 29, no.2 (2017) : 154-173.doi: 10.7730/JSCM.2017.29.2.154
