@article{ART001509391},
author={이진아 and 하혜경 and 이호영 and 정다영 and 이준경 and 황대선 and 신현규},
title={Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2010},
volume={22},
number={4},
pages={56-64}
TY - JOUR
AU - 이진아
AU - 하혜경
AU - 이호영
AU - 정다영
AU - 이준경
AU - 황대선
AU - 신현규
TI - Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2010
VL - 22
IS - 4
PB - The Society of Sasang Constitution and Immune Medicine
SP - 56
EP - 64
SN - 1226-4075
AB - 1. Objectives 4 herbal formulas (Yanggyeoksanhwa-tang, Yeoldahanso-tang, Cheongsimyeonja-tang and Taeeumjowi-tang) were applied to investigate the anti-inflammatory activities. In many studies, plant-derived anti-inflammatory efficacies have been investigate for their potential inhibitory effects on lipopolysaccharide (LPS)-stimulated macrophages. This study was performed to examine the anti-inflammatory activities of 4 herbal formulas on LPS-stimulated RAW 264.7 cells.
2. Methods The productions of nitric oxide (NO), prostaglandin (PG)E2, interleukin(IL)-6 and tumor necrosis factor (TNF)-α were examined in the presence of the 4 herbal formulas in RAW 264.7 cells. The cells were incubated with LPS 1 μg/mL and 4 herbal formulas for 18 hrs. The anti-inflammatory activity of 4 herbal formulas were investigate by carrageenin-induced paw edema in rats. The paw volume was measured at 2 and 4 hrs following carrageenin- induced paw edema in rats.
3. Results Yanggyeoksanhwa-tang and Cheongsimyeonja-tang showed inhibitory effect on PGE2 production in LPS-stimulated RAW 264.7 cells and a reduction in carrageenin-induced paw edema on rats. Yanggyeoksanhwa-tang showed inhibi- tory effect on IL-6 in LPS-stimulated RAW 264.7 cells. 4 herbal formulas not affect on NO and TNF-α inhibition in LPS-stimulated RAW 264.7 cells.
4. Conclusions These results suggested that Yanggyeoksanhwa-tang and Cheongsimyeonja-tang have anti-inflammatory activity.
KW - Yanggyeoksanhwa-tang (Lianggesanhuo-tang);Yeoldahanso-tang (Reduohanshao-tang);Cheongsimyeonja-tang (Qingxinlianzi-tang);Taeeumjowi-tang (Taiyintiaowei-tang);Anti-inflammation
DO -
UR -
ER -
이진아, 하혜경, 이호영, 정다영, 이준경, 황대선 and 신현규. (2010). Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine. Journal of Sasang Constitution and Immune Medicine, 22(4), 56-64.
이진아, 하혜경, 이호영, 정다영, 이준경, 황대선 and 신현규. 2010, "Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine", Journal of Sasang Constitution and Immune Medicine, vol.22, no.4 pp.56-64.
이진아, 하혜경, 이호영, 정다영, 이준경, 황대선, 신현규 "Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine" Journal of Sasang Constitution and Immune Medicine 22.4 pp.56-64 (2010) : 56.
이진아, 하혜경, 이호영, 정다영, 이준경, 황대선, 신현규. Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine. 2010; 22(4), 56-64.
이진아, 하혜경, 이호영, 정다영, 이준경, 황대선 and 신현규. "Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine" Journal of Sasang Constitution and Immune Medicine 22, no.4 (2010) : 56-64.
이진아; 하혜경; 이호영; 정다영; 이준경; 황대선; 신현규. Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine. Journal of Sasang Constitution and Immune Medicine, 22(4), 56-64.
이진아; 하혜경; 이호영; 정다영; 이준경; 황대선; 신현규. Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine. Journal of Sasang Constitution and Immune Medicine. 2010; 22(4) 56-64.
이진아, 하혜경, 이호영, 정다영, 이준경, 황대선, 신현규. Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine. 2010; 22(4), 56-64.
이진아, 하혜경, 이호영, 정다영, 이준경, 황대선 and 신현규. "Anti-inflammatory Activities of Herbal Formulas for Sasang Constitutional Medicine" Journal of Sasang Constitution and Immune Medicine 22, no.4 (2010) : 56-64.