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@article{ART001591116},
author={최재송 and Nayoung， Bae and TaekWon ahn},
title={The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2011},
volume={23},
number={3},
pages={374-390}

TY - JOUR
AU - 최재송
AU - Nayoung， Bae
AU - TaekWon ahn
TI - The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2011
VL - 23
IS - 3
PB - The Society of Sasang Constitution and Immune Medicine
SP - 374
EP - 390
SN - 1226-4075
AB - 1. Objectives The purpose of this study is to investigate the effect of Suhwagije-tang(SGT) distillate on the immune activity of spleen cells of aged SD rats. 2. Methods We used 10, 50, 72 weeks old SD rats in this study. Spleen cells from SD rats were stimulated with ConA and treated with 1% Vitamin C(Vit.C) or Suhwagijetang distillate(SGT). After 24 hours, the concentrations of IL-2, IL-4,IL-10, IFN-γ in the cell culture supernatant were measured by ELISA. 3. Results and Conclusions 1) At all concentration of SGT distillate, survival rates of liver cells were higher than the control group. In addition,50% SGT distillate group's cell survival rates were significantly higher than other groups. 2) In 10 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group, Vit.C group. In 52 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group. 3) In 10, 52 weeks SD rats(SGT group), the concentration of IL-4 significantly decreased in comparison with ConA group. 4) In 10 weeks SD rats(SGT group), the concentration of IL-10 significantly decreased in comparison with ConA group. And in 72 weeks SD rats(SGT group), the concentration of IL-10 significantly increased in comparison with Vit.C group. 5) In 52, 72 weeks SD rats(SGT group), the concentration of IFN-γ significantly decreased in comparison with 10 weeks SD rats(SGT group). These results suggest that Suhwagije-tang(SGT) distillate has the effect of increasing the immune activity of spleen cells of aged SD rats.
KW - Suhwagije-tang;Immune activity;Spleen cells;Cytokine;Aged rats.
DO -
UR -
ER -

최재송, Nayoung， Bae and TaekWon ahn. (2011). The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats. Journal of Sasang Constitution and Immune Medicine, 23(3), 374-390.

최재송, Nayoung， Bae and TaekWon ahn. 2011, "The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats", Journal of Sasang Constitution and Immune Medicine, vol.23, no.3 pp.374-390.

최재송, Nayoung， Bae, TaekWon ahn "The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats" Journal of Sasang Constitution and Immune Medicine 23.3 pp.374-390 (2011) : 374.

최재송, Nayoung， Bae, TaekWon ahn. The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats. 2011; 23(3), 374-390.

최재송, Nayoung， Bae and TaekWon ahn. "The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats" Journal of Sasang Constitution and Immune Medicine 23, no.3 (2011) : 374-390.

최재송; Nayoung， Bae; TaekWon ahn. The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats. Journal of Sasang Constitution and Immune Medicine, 23(3), 374-390.

최재송; Nayoung， Bae; TaekWon ahn. The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats. Journal of Sasang Constitution and Immune Medicine. 2011; 23(3) 374-390.

최재송, Nayoung， Bae, TaekWon ahn. The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats. 2011; 23(3), 374-390.

최재송, Nayoung， Bae and TaekWon ahn. "The Effect of Suhwagije-tang Distillate on the Immune Activity of Spleen Cells of Aged Rats" Journal of Sasang Constitution and Immune Medicine 23, no.3 (2011) : 374-390.