@article{ART002707530},
author={Ahn Bo-kook and Jeong-Mo Song},
title={Anti-allergy Action of Soeumin Kwakhyangjeonggisan},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2001},
volume={13},
number={3},
pages={75-88}
TY - JOUR
AU - Ahn Bo-kook
AU - Jeong-Mo Song
TI - Anti-allergy Action of Soeumin Kwakhyangjeonggisan
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2001
VL - 13
IS - 3
PB - The Society of Sasang Constitution and Immune Medicine
SP - 75
EP - 88
SN - 1226-4075
AB - The purpose of this research was to investigate the effects of Kwakhyangjeonggisan (KJS) on the anti-allergic action. In the present study, we examined the effect of KJS on type I and type IV allergic reaction. KJS inhibited the systemic anaphylaxis induced by compound 48/80 and platelet activating factor (PAF), and inhibited the passive cutaneous anaphylaxis (PCA) induced by anti-dinitrophenyl (DNP)-IgE and DNP-human serum albumin (HSA) in vivo. In addition, KJS dose-dependently inhibited the release of histamine from peritoneal mast cells in rat. Also, KJS inhibited the delayed type hypersensitivity (DTH) induced by SRBC and the contact dermatitis induced by dinitrofluorobenzene (DNFB). KJS inhibited the proliferation of splenocytes, the subpopulation of B220+ cells and CD4+CD8-(Th) cells in splenocytes and the production of γ-interferon in serum and splenocytes. These findings suggest that KJS prevented the type I allergy by the inhibition of histamine release from mast cells and the type IV allergy by the inhibition of γ-interferon production and B lymphocytes subpopulation. These results indicate that KJS may be useful for the prevention and treatment of type I and type IV allergy related disease.
KW - Kwakhyangjeonggisan(KJS);I allergy;IV allergy;prevention
DO -
UR -
ER -
Ahn Bo-kook and Jeong-Mo Song. (2001). Anti-allergy Action of Soeumin Kwakhyangjeonggisan. Journal of Sasang Constitution and Immune Medicine, 13(3), 75-88.
Ahn Bo-kook and Jeong-Mo Song. 2001, "Anti-allergy Action of Soeumin Kwakhyangjeonggisan", Journal of Sasang Constitution and Immune Medicine, vol.13, no.3 pp.75-88.
Ahn Bo-kook, Jeong-Mo Song "Anti-allergy Action of Soeumin Kwakhyangjeonggisan" Journal of Sasang Constitution and Immune Medicine 13.3 pp.75-88 (2001) : 75.
Ahn Bo-kook, Jeong-Mo Song. Anti-allergy Action of Soeumin Kwakhyangjeonggisan. 2001; 13(3), 75-88.
Ahn Bo-kook and Jeong-Mo Song. "Anti-allergy Action of Soeumin Kwakhyangjeonggisan" Journal of Sasang Constitution and Immune Medicine 13, no.3 (2001) : 75-88.
Ahn Bo-kook; Jeong-Mo Song. Anti-allergy Action of Soeumin Kwakhyangjeonggisan. Journal of Sasang Constitution and Immune Medicine, 13(3), 75-88.
Ahn Bo-kook; Jeong-Mo Song. Anti-allergy Action of Soeumin Kwakhyangjeonggisan. Journal of Sasang Constitution and Immune Medicine. 2001; 13(3) 75-88.
Ahn Bo-kook, Jeong-Mo Song. Anti-allergy Action of Soeumin Kwakhyangjeonggisan. 2001; 13(3), 75-88.
Ahn Bo-kook and Jeong-Mo Song. "Anti-allergy Action of Soeumin Kwakhyangjeonggisan" Journal of Sasang Constitution and Immune Medicine 13, no.3 (2001) : 75-88.
