@article{ART002763765},
author={Ok Yun-young and Kim Jong-kwan and Han Byung-sam and kim kyung yo and Go Gi-Deok},
title={Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2002},
volume={14},
number={1},
pages={123-131}
TY - JOUR
AU - Ok Yun-young
AU - Kim Jong-kwan
AU - Han Byung-sam
AU - kim kyung yo
AU - Go Gi-Deok
TI - Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2002
VL - 14
IS - 1
PB - The Society of Sasang Constitution and Immune Medicine
SP - 123
EP - 131
SN - 1226-4075
AB - Glutathione S-transferase polymorphisms (GST) were examined in 98 cases with cerebrovascular disease (CVD) to test the hypothesis that GST polymorphisms confer a risk to an individual to develop CVD. Tobacco smoke is a major cause of both cancer and vascular disease. We therefore were stratified the subjects with CVD for smoking status, and then examined whether polymorphisms in this detoxification enzyme gene, GST, influence risk of CVD. Neither GSTM1 nor GSTT1 genotypes in the CVD group was significantly different from the control group (n=230), even in smokers. We attempted the combined analyses for GSTM1 and GSTT1 genotypes in CVD for smoking status. No significant association observed between the combined genotypes and CVD. We also classified the subjects and control group into four types according to Sasang Constitutional Medicine, Korean Traditional Oriental Medicine, and investigated the association among GST genotypes, CVD, and Sasang constitutional classification. Our observations do not confirm the effect of the GSTM1 and GSTT1 genotypes as a risk factor for CVD, even in smokers. Furthermore, we first attempted to evaluate the efficacy of Sasang Constitutional Medicine, and to find an association with CVD.
KW - GST;CVD;cerebrovascular;disease;glutathione;S-transferase;polymorphism;Sasang constitution;cerebrovascular disease;glutathione S-transferase
DO -
UR -
ER -
Ok Yun-young, Kim Jong-kwan, Han Byung-sam, kim kyung yo and Go Gi-Deok. (2002). Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution. Journal of Sasang Constitution and Immune Medicine, 14(1), 123-131.
Ok Yun-young, Kim Jong-kwan, Han Byung-sam, kim kyung yo and Go Gi-Deok. 2002, "Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution", Journal of Sasang Constitution and Immune Medicine, vol.14, no.1 pp.123-131.
Ok Yun-young, Kim Jong-kwan, Han Byung-sam, kim kyung yo, Go Gi-Deok "Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution" Journal of Sasang Constitution and Immune Medicine 14.1 pp.123-131 (2002) : 123.
Ok Yun-young, Kim Jong-kwan, Han Byung-sam, kim kyung yo, Go Gi-Deok. Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution. 2002; 14(1), 123-131.
Ok Yun-young, Kim Jong-kwan, Han Byung-sam, kim kyung yo and Go Gi-Deok. "Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution" Journal of Sasang Constitution and Immune Medicine 14, no.1 (2002) : 123-131.
Ok Yun-young; Kim Jong-kwan; Han Byung-sam; kim kyung yo; Go Gi-Deok. Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution. Journal of Sasang Constitution and Immune Medicine, 14(1), 123-131.
Ok Yun-young; Kim Jong-kwan; Han Byung-sam; kim kyung yo; Go Gi-Deok. Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution. Journal of Sasang Constitution and Immune Medicine. 2002; 14(1) 123-131.
Ok Yun-young, Kim Jong-kwan, Han Byung-sam, kim kyung yo, Go Gi-Deok. Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution. 2002; 14(1), 123-131.
Ok Yun-young, Kim Jong-kwan, Han Byung-sam, kim kyung yo and Go Gi-Deok. "Interrelationships among Glutathione S-Transferase Polymorphisms, Cerebrovascular Disease and Sasang Constitution" Journal of Sasang Constitution and Immune Medicine 14, no.1 (2002) : 123-131.
