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Genetic Analysis study of Sasang Constitution Classification by DNA-fingerprinting methods

  • Journal of Sasang Constitutional Medicine
  • Abbr : J Sasang Constitut Med
  • 1996, 8(2), pp.151-163
  • Publisher : The Society Of Sasang Constitutional Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : December 31, 1996
  • Accepted : December 31, 1996
  • Published : December 31, 1996

Cho Dong-wuk 1 Lee Chang Soo 2 Koh Byung-Hee 3 Cho, Hwang-Sung 4

1한국한의학연구원
2건국대학교
3경희대학교 한의과대학 사상체질과
4대한한의학회

ABSTRACT

VNTR and STR DNA typing are typical genetic analysis methods which are widely used in DNA-fingerprinting for forensic science and other genetic research purposes. In this study, genomic DNA of different constitutions(Taeun, Soyang and Soum) were analyzed by VNTR and STR DNA typing to provide scientific and objective references for Sasang Medicine. It was found out in this study that VNTR-MCT118 and YNZ22 loci showed too many different variation of allele distribution and numbers for each constitution. Therefore, it is thought that VNTR typing can not used for genetic classification study for Sasang Constitution which classifies human body into 4 groups. However, vWA locus, one of the STR loci investigated in this study, showed slight difference in allele distribution for each different constitution.

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