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Controlled Release Behavior of pH-Responsive Composite Hydrogel Containing Activated Carbon

  • Carbon Letters
  • Abbr : Carbon Lett.
  • 2009, 10(1), pp.33-37
  • Publisher : Korean Carbon Society
  • Research Area : Natural Science > Natural Science General > Other Natural Sciences General

윤주미 1 Im Ji Sun 1 오예리 1 Lee, Young-Seak 1 김형일 1

1충남대학교

Candidate

ABSTRACT

Activated carbon (AC) is one of the most effective adsorbents for organic compounds because of their extended surface area, high adsorption capacity, microporous structure and special surface reactivity. The composites of pH-sensitive hydrogel and activated carbon were prepared in order to improve the loading capacity of drug. The pH-sensitive hydrogel matrix swelled well in the basic condition to release the drug loaded in AC. The release of drug was controlled depending on both the pH due to the ionization of the carboxylic acid group and the AC due to the surface properties.

Citation status

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This paper was written with support from the National Research Foundation of Korea.