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@article{ART001683690},
author={Xu Liang Deng and Xiao Ping Yang},
title={Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration},
journal={Carbon Letters},
issn={1976-4251},
year={2012},
volume={13},
number={3},
pages={139-150},
doi={10.5714/CL.2012.13.3.139}

TY - JOUR
AU - Xu Liang Deng
AU - Xiao Ping Yang
TI - Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration
JO - Carbon Letters
PY - 2012
VL - 13
IS - 3
PB - Korean Carbon Society
SP - 139
EP - 150
SN - 1976-4251
AB - Poly-L-lactic acid (PLLA), PLLA/hydroxyapatite (HA), PLLA/multiwalled carbon nanotubes (MWNTs)/HA, PLLA/trifluoroethanol (TFE), PLLA/gelatin, and carbon nanofibers (CNFs)/β-tricalcium phosphate (β-TCP) composite membranes (scaffolds) were fabricated by electrospinning and their morphologies, and mechanical properties were characterized for use in bone tissue regeneration/guided tissue regeneration. MWNTs and HA nanoparticles were well distributed in the membranes and the degradation characteristics were improved. PLLA/MWNTs/HA membranes enhanced the adhesion and proliferation of periodontal ligament cells (PDLCs) by 30% and inhibited the adhesion of gingival epithelial cells by 30%. Osteoblast-like MG-63 cells on the randomly fiber oriented PLLA/TEF membrane showed irregular forms, while the cells exhibited shuttle-like shapes on the parallel fiber oriented membrane. Classical supersaturated simulated body fluids were modified by CO2 bubbling and applied to promote the biomineralization of the PLLA/gelatin membrane; this resulted in predictions of bone bonding bioactivity of the substrates. The β-TCP membranes exhibit good biocompatibility, have an effect on PDLC growth comparable to that of pure CNF membrane, and can be applied as scaffolds for bone tissue regeneration.
KW - composite membrane;scaffold;periodontal ligament cell;bone tissue regeneration;simulated body fluid;biocompatibility
DO - 10.5714/CL.2012.13.3.139
ER -

Xu Liang Deng and Xiao Ping Yang. (2012). Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration. Carbon Letters, 13(3), 139-150.

Xu Liang Deng and Xiao Ping Yang. 2012, "Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration", Carbon Letters, vol.13, no.3 pp.139-150. Available from: doi:10.5714/CL.2012.13.3.139

Xu Liang Deng, Xiao Ping Yang "Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration" Carbon Letters 13.3 pp.139-150 (2012) : 139.

Xu Liang Deng, Xiao Ping Yang. Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration. 2012; 13(3), 139-150. Available from: doi:10.5714/CL.2012.13.3.139

Xu Liang Deng and Xiao Ping Yang. "Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration" Carbon Letters 13, no.3 (2012) : 139-150.doi: 10.5714/CL.2012.13.3.139

Xu Liang Deng; Xiao Ping Yang. Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration. Carbon Letters, 13(3), 139-150. doi: 10.5714/CL.2012.13.3.139

Xu Liang Deng; Xiao Ping Yang. Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration. Carbon Letters. 2012; 13(3) 139-150. doi: 10.5714/CL.2012.13.3.139

Xu Liang Deng, Xiao Ping Yang. Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration. 2012; 13(3), 139-150. Available from: doi:10.5714/CL.2012.13.3.139

Xu Liang Deng and Xiao Ping Yang. "Fabrication and Cell Culturing on Carbon Nanofibers/ Nanoparticles Reinforced Membranes for Bone-Tissue Regeneration" Carbon Letters 13, no.3 (2012) : 139-150.doi: 10.5714/CL.2012.13.3.139