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Highly sensitive electrochemical detection of melatonin based on graphene-assisted molecular imprinting technology

  • Carbon Letters
  • Abbr : Carbon Lett.
  • 2024, 34(1), pp.437-444
  • DOI : 10.1007/s42823-023-00504-4
  • Publisher : Korean Carbon Society
  • Research Area : Natural Science > Natural Science General > Other Natural Sciences General
  • Received : February 9, 2023
  • Accepted : March 23, 2023
  • Published : February 1, 2024

Sun Bin 1 Sun Wei 2 Wang Zhigang 1 Zhao Bo 3 Yang Song 3

1Department of Neurosurgery, Cheeloo College of Medicine, Qilu Hospital (Qingdao), Shandong University
2Department of Neurology, Third People’s Hospital of Qingdao
3Department of Neurosurgery, Jiaozhou Branch, East Hospital of Tongji University

Accredited

ABSTRACT

In this paper, a simple, cost-effective, and efficient electrochemical sensor for molecular imprinting melatonin was established. The molecular imprinted films were formed by in situ electrochemical polymerization using molecular imprinting technology. The modification method, modification time and other parameters of the electrode were optimized. Under optimized conditions, the sensor responds to melatonin concentration in a linear range of 0–100 μM. The detection limit was 0.171 μM. In addition, the sensor has little response to interfering substances, such as uric acid, vitamin B6, vitamin C, and glucose, and can be tested in real samples. The recoveries were 98.73–101.60%.

Citation status

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