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Simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid using Au decorated carbon nanofibers modified screen printed electrode

  • Carbon Letters
  • Abbr : Carbon Lett.
  • 2024, 34(9), pp.2325-2341
  • DOI : 10.1007/s42823-024-00759-5
  • Publisher : Korean Carbon Society
  • Research Area : Natural Science > Natural Science General > Other Natural Sciences General
  • Received : March 27, 2024
  • Accepted : May 31, 2024
  • Published : December 5, 2024

Sakthivel P. 1 Ramachandran K. 1 Maheshvaran K. 2 Senthil T. S. 3 Manivel P. 3

1Department of Chemistry, Builders Engineering College, Tiruppur
2Department of Physics, Kongu Engineering College
3Centre for Nanotechnology, Erode Sengunthar Engineering

Accredited

ABSTRACT

Gold nanoparticles (Au NPs) decorated carbon nanofibers (CNFs) have been prepared by an electrospinning approach and then carbonized. The prepared Au-CNFs were employed to modifying a screen printed electrode (SPE) for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). Au NPs are uniformly dispersed on carbon nanofibers were confirmed by the structure and morphological studies. The modified electrodes were tested in cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA) to characterize their electrochemical responses. Compared to bare SPE, the Au-CNFs/SPE had a better sensing response to AA, DA, and UA. The electrochemical oxidation signal of AA, DA and UA are well separated into three distinct peaks with peak potential separation of 280 mV, 159 mV and 439 mV between AA-DA, DA-UA and AA-UA respectively in CV studies and the corresponding peak potential separation in DPV studies are 290 mV, 166 mV and 456 mV. The Au-CNFs/SPE has a wide linear response of AA, DA and UA in DPV analysis over the range of 5–40 µM (R2 = 0.9984), 2–16 µM (R2 = 0.9962) and 2–16 µM (R2 = 0.9983) with corresponding detection limits of 0.9 µM, 0.4 µM and 0.3 µM at S/N = 3, respectively. The developed modified SPE based sensor exhibits excellent reproducibility, stability, and repeatability. The excellent sensing response of Au-CNFs could reveal to a promising approach in electrochemical sensor.

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