KJCKorea
Journal Central

@article{ART002167115},
author={김은지 and Mi-Hye Kim},
title={Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models},
journal={CELLMED},
issn={3022-6805},
year={2016},
volume={6},
number={4},
pages={28-28},
doi={10.5667/tang.2016.0025}

TY - JOUR
AU - 김은지
AU - Mi-Hye Kim
TI - Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models
JO - CELLMED
PY - 2016
VL - 6
IS - 4
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 28
EP - 28
SN - 3022-6805
AB - Oxidative rancidity in foods causes undesirable changes in nutritive value, aroma, flavor, and color. Salix Koreensis Andersson in DC. (SK) has anti-oxidative and anti-inflammatory effects and is traditionally used to treat neuralgia, edema, pain, and inflammatory diseases. However, the regulatory effects of SK on oxidative and inflammatory reactions have not been elucidated. In this context, we scientifically validated the anti-oxidative and anti-inflammatory activities of SK leaf (SKL). The methanol extract of SKL was evaluated for in vitro anti-oxidative activities. SKL showed increased superoxide dismutase (SOD)-like activity and 1, 1-diphenyl-2-picrylhydrazyl radical scavenging activity. The in vitro anti-oxidant and anti-inflammatory activities of SKL were also investigated in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. LPS resulted in decreased SOD activities compared with the unstimulated cells, but SKL significantly increased SOD activities reduced by LPS. In addition, LPS-induced nitric oxide, tumor necrosis factor-α, and interleukin-6 productions were significantly and dose-dependently reduced by SKL in RAW264.7 macrophages without inducing cytotoxicity. In conclusion, these results indicate that SKL will be able to be effectively used as a food additive with anti-oxidative and anti-inflammatory effects.
KW - Salix Koreensis Andersson in DC.;anti-oxidant activity;anti-inflammatory activity;superoxide dismutase
DO - 10.5667/tang.2016.0025
ER -

김은지 and Mi-Hye Kim. (2016). Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models. CELLMED, 6(4), 28-28.

김은지 and Mi-Hye Kim. 2016, "Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models", CELLMED, vol.6, no.4 pp.28-28. Available from: doi:10.5667/tang.2016.0025

김은지, Mi-Hye Kim "Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models" CELLMED 6.4 pp.28-28 (2016) : 28.

김은지, Mi-Hye Kim. Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models. 2016; 6(4), 28-28. Available from: doi:10.5667/tang.2016.0025

김은지 and Mi-Hye Kim. "Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models" CELLMED 6, no.4 (2016) : 28-28.doi: 10.5667/tang.2016.0025

김은지; Mi-Hye Kim. Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models. CELLMED, 6(4), 28-28. doi: 10.5667/tang.2016.0025

김은지; Mi-Hye Kim. Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models. CELLMED. 2016; 6(4) 28-28. doi: 10.5667/tang.2016.0025

김은지, Mi-Hye Kim. Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models. 2016; 6(4), 28-28. Available from: doi:10.5667/tang.2016.0025

김은지 and Mi-Hye Kim. "Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models" CELLMED 6, no.4 (2016) : 28-28.doi: 10.5667/tang.2016.0025