@article{ART002250898},
author={장재범 and Tae-Young Kim and Hyun-Ja Jeong and Hyung-Min Kim},
title={Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01},
journal={CELLMED},
issn={3022-6805},
year={2017},
volume={7},
number={3},
pages={14-14}
TY - JOUR
AU - 장재범
AU - Tae-Young Kim
AU - Hyun-Ja Jeong
AU - Hyung-Min Kim
TI - Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01
JO - CELLMED
PY - 2017
VL - 7
IS - 3
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 14
EP - 14
SN - 3022-6805
AB - Rumex crispus (RC) or Cordyceps militaris (CM) has been used traditionally to treat various diseases and has been also consumed as a functional food made by humanitas medicine concept. We prepared a new herbal mixture, AST2017-01 which is mainly composed of processed (Beopje)-RC (P-RC) and -CM (P-CM). This study aims to validate marker compounds (chrysophanol and cordycepin) in P-RC and P-CM and water extracted-RC and -CM using liquid chromatography-tandem mass spectrometry. In addition, we analyzed contents of chrysophanol and cordycepin in AST2017-01. The linarites of chrysophanol and cordycepin were obtained in calibration curve with a coefficient of correlation of 0.999. The results showed that the concentrations of chrysophanol and cordycepin in P-RC and P-CM were almost 1.70 and 1.23 fold higher than that in RC and CM, respectively. Furthermore, contents of chrysophanol and cordycepin in the AST2017-01 are approximately 0.13% and 0.028%, respectively. In conclusion, these results indicate that chrysophanol and cordycepin were validated as marker compounds in the AST2017-01.
KW - Rumex crispus;Cordyceps militaris;liquid chromatography-tandem mass spectrometry;chrysophanol;cordycepin
DO -
UR -
ER -
장재범, Tae-Young Kim, Hyun-Ja Jeong and Hyung-Min Kim. (2017). Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01. CELLMED, 7(3), 14-14.
장재범, Tae-Young Kim, Hyun-Ja Jeong and Hyung-Min Kim. 2017, "Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01", CELLMED, vol.7, no.3 pp.14-14.
장재범, Tae-Young Kim, Hyun-Ja Jeong, Hyung-Min Kim "Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01" CELLMED 7.3 pp.14-14 (2017) : 14.
장재범, Tae-Young Kim, Hyun-Ja Jeong, Hyung-Min Kim. Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01. 2017; 7(3), 14-14.
장재범, Tae-Young Kim, Hyun-Ja Jeong and Hyung-Min Kim. "Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01" CELLMED 7, no.3 (2017) : 14-14.
장재범; Tae-Young Kim; Hyun-Ja Jeong; Hyung-Min Kim. Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01. CELLMED, 7(3), 14-14.
장재범; Tae-Young Kim; Hyun-Ja Jeong; Hyung-Min Kim. Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01. CELLMED. 2017; 7(3) 14-14.
장재범, Tae-Young Kim, Hyun-Ja Jeong, Hyung-Min Kim. Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01. 2017; 7(3), 14-14.
장재범, Tae-Young Kim, Hyun-Ja Jeong and Hyung-Min Kim. "Validation of chrysophanol and cordycepin as marker compounds for standardization of a new herbal mixture AST2017-01" CELLMED 7, no.3 (2017) : 14-14.