@article{ART002250899},
author={SongGylHoon and EUI SEONG PARK and Seung-Min Lee and Tae-Young Kim and PARK,KUN-YOUNG},
title={An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells},
journal={CELLMED},
issn={3022-6805},
year={2017},
volume={7},
number={3},
pages={15-15}
TY - JOUR
AU - SongGylHoon
AU - EUI SEONG PARK
AU - Seung-Min Lee
AU - Tae-Young Kim
AU - PARK,KUN-YOUNG
TI - An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells
JO - CELLMED
PY - 2017
VL - 7
IS - 3
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 15
EP - 15
SN - 3022-6805
AB - We analyzed the effects of an Atopic Preventive Drink (APD) on the regulation of Th2 cytokines using RAW 264.7 macrophage cells. In the evaluation of nitric oxide (NO) production in cells, NO production levels were shown to be elevated only in the APD-treated group in a dose-dependent manner. In the lipopolysaccharide (LPS) with APD-treated group, NO production significantly decreased as APD concentration increased. Further, mRNA expression levels and protein concentrations of pro-inflammatory cytokines in cells were determined. Th2 stimulatory cytokine (IL-1β) and Th2 cytokine (IL-6 and IL-10) levels were significantly reduced in the LPS with APD-treated group compared to the only LPS-treated group. mRNA expression levels of inflammatory-related genes (COX-2 and iNOS) were significantly reduced in the LPS with APD-treated group compared to the only LPS-treated group. These results suggest that APD has an anti-atopic effect by reducing mRNA and proteins expressions of Th2 cytokines and inflammatory-related genes.
KW - Atopic Preventive Drink;Th2 cytokines;lipopolysaccharides;RAW 264.7 cells
DO -
UR -
ER -
SongGylHoon, EUI SEONG PARK, Seung-Min Lee, Tae-Young Kim and PARK,KUN-YOUNG. (2017). An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells. CELLMED, 7(3), 15-15.
SongGylHoon, EUI SEONG PARK, Seung-Min Lee, Tae-Young Kim and PARK,KUN-YOUNG. 2017, "An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells", CELLMED, vol.7, no.3 pp.15-15.
SongGylHoon, EUI SEONG PARK, Seung-Min Lee, Tae-Young Kim, PARK,KUN-YOUNG "An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells" CELLMED 7.3 pp.15-15 (2017) : 15.
SongGylHoon, EUI SEONG PARK, Seung-Min Lee, Tae-Young Kim, PARK,KUN-YOUNG. An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells. 2017; 7(3), 15-15.
SongGylHoon, EUI SEONG PARK, Seung-Min Lee, Tae-Young Kim and PARK,KUN-YOUNG. "An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells" CELLMED 7, no.3 (2017) : 15-15.
SongGylHoon; EUI SEONG PARK; Seung-Min Lee; Tae-Young Kim; PARK,KUN-YOUNG. An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells. CELLMED, 7(3), 15-15.
SongGylHoon; EUI SEONG PARK; Seung-Min Lee; Tae-Young Kim; PARK,KUN-YOUNG. An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells. CELLMED. 2017; 7(3) 15-15.
SongGylHoon, EUI SEONG PARK, Seung-Min Lee, Tae-Young Kim, PARK,KUN-YOUNG. An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells. 2017; 7(3), 15-15.
SongGylHoon, EUI SEONG PARK, Seung-Min Lee, Tae-Young Kim and PARK,KUN-YOUNG. "An Atopic Preventive Drink (APD) reduces Th2 cytokines in LPS-treated RAW 264.7 cells" CELLMED 7, no.3 (2017) : 15-15.