A comparison study of the effects of loratadine-pharmacopuncture and loratadine-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice

Hyun-Min Kim; Hyun-Min Kim; Min-Jung Lee; Min-Gi Cho; Deok Kang; Yu-Kyung Kim; et al.; Phil-Dong Moon

A comparison study of the effects of loratadine-pharmacopuncture and loratadine-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice

CELLMED
Abbr : CellMed
2018, 8(1), pp.5~5
Publisher : Cellmed Orthocellular Medicine and Pharmaceutical Association
Research Area : Medicine and Pharmacy > General Medicine

Hyun-Min Kim ¹, Hyun-Min Kim ¹, Min-Jung Lee ¹, Min-Gi Cho ¹, Deok Kang ¹, Yu-Kyung Kim ¹, et al. ¹, Phil-Dong Moon ¹

¹Kyung Hee University

Candidate

ABSTRACT

Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between loratadine-pharmacopuncture (LP) and loratadine-oral administration (LO), the effect of loratadine was investigated in murine models. Anti-anaphylactic effects of loratadine treatments were investigated in compound 48/80-induced systemic anaphylactic reaction and passive cutaneous anaphylaxis (PCA). LP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction and PCA. The effect between LP and LO were on a similar level. These results indicate that LP can be used as an alternative method for LO in case of emergency.

KEYWORDS

loratadine-pharmacopuncture, systemic anaphylactic reaction, passive cutaneous anaphylaxis

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