@article{ART002525348},
author={Arun K. Yadav and Risa Parkordor Chen},
title={Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.},
journal={CELLMED},
issn={3022-6805},
year={2019},
volume={9},
number={4},
pages={9-9}
TY - JOUR
AU - Arun K. Yadav
AU - Risa Parkordor Chen
TI - Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.
JO - CELLMED
PY - 2019
VL - 9
IS - 4
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 9
EP - 9
SN - 3022-6805
AB - Ayurveda is one of the ancient systems of traditional medicine in India, however, there is a lack of proper scientific research and controlled studies on efficacy and toxicity of several Ayurvedic formulations using the methods of modern science, which hinders the proper development of Ayurveda, both in India and abroad. The present study was undertaken to further corroborate the efficacy of some popular anthelmintic Ayurvedic medicines, as evident by the pharmacological effects of Ayurvedic formulations on body surface of a cestode parasite. This study employed a common intestinal cestode of domestic fowl, Raillietina sp., as a model parasite, that was exposed in vitro to different concentrations of three common Indian Ayurvedic anthelmintic drugs, namely Krimimudgar Ras, Kriminol and Vidangasava, and also to a modern anthelmintic drug, praziquantel (PZQ). After the paralysis of parasites, the specimens from the highest drug-treated concentration (50 mg/ml), praziquantel (1 mg/ml), and control groups, were collected and processed for scanning electron microscopic studies to document the effects of drugs on the body surface of parasite. In this study, maximum degree of alterations on parasite body surface was observed in the worms exposed to Krimimudgar Ras, indicating this drug to be highly efficacious against intestinal worms and brings out a transtegumental mode of action on parasite. In conclusion, the findings of present study suggest that of the three Ayurvedic formulations tested, Krimimudgar Ras possesses significant anthelmintic effects, which are mediated through parasite’s body surface. Therefore, Krimimudgar Ras may be considered as a reliable anthelmintic Ayurvedic formulation, as validated through this study.
KW - Ayurvedic drugs;Electron microscopy;Helminthic disease;Krimi roga;Krimimudgar Ras;Kriminol;Vidangasava
DO -
UR -
ER -
Arun K. Yadav and Risa Parkordor Chen. (2019). Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.. CELLMED, 9(4), 9-9.
Arun K. Yadav and Risa Parkordor Chen. 2019, "Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.", CELLMED, vol.9, no.4 pp.9-9.
Arun K. Yadav, Risa Parkordor Chen "Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp." CELLMED 9.4 pp.9-9 (2019) : 9.
Arun K. Yadav, Risa Parkordor Chen. Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.. 2019; 9(4), 9-9.
Arun K. Yadav and Risa Parkordor Chen. "Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp." CELLMED 9, no.4 (2019) : 9-9.
Arun K. Yadav; Risa Parkordor Chen. Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.. CELLMED, 9(4), 9-9.
Arun K. Yadav; Risa Parkordor Chen. Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.. CELLMED. 2019; 9(4) 9-9.
Arun K. Yadav, Risa Parkordor Chen. Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp.. 2019; 9(4), 9-9.
Arun K. Yadav and Risa Parkordor Chen. "Scanning electron microscopic effects of Indian Ayurvedic drugs: Krimimudgar Ras, Kriminol and Vidangasava on a tapeworm, Raillietina sp." CELLMED 9, no.4 (2019) : 9-9.