@article{ART003338695},
author={Bong-Keun Jang and Sung-Bae Lee and Youngsun Kwon and Hye-Yeon Kang},
title={Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells},
journal={CELLMED},
issn={3022-6805},
year={2026},
volume={16},
number={4},
pages={17-22},
doi={10.5667/CellMed.2026.006}
TY - JOUR
AU - Bong-Keun Jang
AU - Sung-Bae Lee
AU - Youngsun Kwon
AU - Hye-Yeon Kang
TI - Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells
JO - CELLMED
PY - 2026
VL - 16
IS - 4
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 17
EP - 22
SN - 3022-6805
AB - Objective: Oxidative stress and alcohol-induced hepatocellular injury are major contributors to the development of liver disorders.
Method: The protective effects of Bovitacin Lipa were evaluated in hydrogen peroxide (H₂O₂)- and ethanol (EtOH)-induced cytotoxicity models using HepG2 cells.
Result: Exposure of HepG2 cells to H₂O₂ (1 mM) or EtOH (100 mM) significantly reduced cell viability while treatment with Bovitacin Lipa at concentrations ranging from 10 to 500 μg/mL markedly and dose-dependently restored cell viability under both stress conditions. At higher concentrations, cell viability approached levels comparable to normal control.
Conclusion: These results suggest that Bovitacin Lipa exerts a protective effect against oxidative stress- and ethanol-induced hepatocellular injury.
KW - HepG2 cells;oxidative stress;alcohol injury;cell viability;Bovitacin Lipa
DO - 10.5667/CellMed.2026.006
ER -
Bong-Keun Jang, Sung-Bae Lee, Youngsun Kwon and Hye-Yeon Kang. (2026). Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells. CELLMED, 16(4), 17-22.
Bong-Keun Jang, Sung-Bae Lee, Youngsun Kwon and Hye-Yeon Kang. 2026, "Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells", CELLMED, vol.16, no.4 pp.17-22. Available from: doi:10.5667/CellMed.2026.006
Bong-Keun Jang, Sung-Bae Lee, Youngsun Kwon, Hye-Yeon Kang "Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells" CELLMED 16.4 pp.17-22 (2026) : 17.
Bong-Keun Jang, Sung-Bae Lee, Youngsun Kwon, Hye-Yeon Kang. Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells. 2026; 16(4), 17-22. Available from: doi:10.5667/CellMed.2026.006
Bong-Keun Jang, Sung-Bae Lee, Youngsun Kwon and Hye-Yeon Kang. "Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells" CELLMED 16, no.4 (2026) : 17-22.doi: 10.5667/CellMed.2026.006
Bong-Keun Jang; Sung-Bae Lee; Youngsun Kwon; Hye-Yeon Kang. Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells. CELLMED, 16(4), 17-22. doi: 10.5667/CellMed.2026.006
Bong-Keun Jang; Sung-Bae Lee; Youngsun Kwon; Hye-Yeon Kang. Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells. CELLMED. 2026; 16(4) 17-22. doi: 10.5667/CellMed.2026.006
Bong-Keun Jang, Sung-Bae Lee, Youngsun Kwon, Hye-Yeon Kang. Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells. 2026; 16(4), 17-22. Available from: doi:10.5667/CellMed.2026.006
Bong-Keun Jang, Sung-Bae Lee, Youngsun Kwon and Hye-Yeon Kang. "Protective effects of the herbal formula Bovitacin Lipa against hydrogen peroxide- and alcohol-induced cytotoxicity in HepG2 cells" CELLMED 16, no.4 (2026) : 17-22.doi: 10.5667/CellMed.2026.006
