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Studies on Sickle Cell Disease for Case-Based Learning in General Biology Course for Non-Biological Major Students

  • The Journal of General Education
  • 2022, (19), pp.143~173
  • DOI : 10.24173/jge.2022.04.19.6
  • Publisher : Da Vinci Mirae Institute of General Education
  • Research Area : Social Science > Education > Field of Education > General Education
  • Received : March 20, 2022
  • Accepted : April 20, 2022
  • Published : April 30, 2022

Hye Sup Yun 1 Don Ha Park 2 Soo Chul Chang 2

1건국대학교
2연세대학교

Accredited

ABSTRACT

A study has been undertaken to suggest a case which can be used for case-based learning in general biology course for non-biological major students. We chose sickle cell disease as a case for helping students’ understanding genetics concepts such as relationship of chromsomes and genes, dominant and recessive characters, law of segregation and probablity, and pleiotropy. This case also seems to be useful in understanding concepts of mutation in terms of genetics and molecular biology. The same is the case for evolution. Because the gene of this disease and genes of several other blood cell diseases seem to be selected against malaria and so they can be regarded to play roles in evolution of human beings via natural selection. Furthermore sickle cell disease seems to be also helpful to understand several content elements of circulation and immunity. And this disease case is also applicable in newly developing research field, that is, coevolution of culture and gene. Taken together, all of these results demonstrate that sickle cell disease can be used as a very appropriate case in intensive understanding of core concepts such as genetics and evolution which are suggested by 『Vision and Changes』.

Citation status

* References for papers published after 2023 are currently being built.

This paper was written with support from the National Research Foundation of Korea.