Detection of Streptococcus mutans in Saliva using Monoclonal Antibodies (단일클론항체를 사용한 타액 내 Streptococcus mutans 검출)

이민정; Daewoo Lee (이대우); Miah Kim (김미아); Lee Kyung-Yeol (이경열); Byeong Ju Baik (백병주); Yang Yeon Mi (양연미); KIM JAE GON (김재곤)

doi:10.5933/JKAPD.2015.42.1.10

Detection of Streptococcus mutans in Saliva using Monoclonal Antibodies

Journal of the Korean academy of pediatric dentistry
Abbr : J Korean Acad Pediatr Dent
2015, 42(1), pp.10-21
DOI : 10.5933/JKAPD.2015.42.1.10
Publisher : The Korean Academy Of Pediatric Dentistry
Research Area : Medicine and Pharmacy > Dentistry

이민정 ¹, Daewoo Lee ¹, Miah Kim ², Lee Kyung-Yeol ², Byeong Ju Baik ², Yang Yeon Mi ², KIM JAE GON ²

¹전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소
²전북대학교

Accredited

ABSTRACT

The purpose of this study was to determine the usefulness of a detection method for Streptococcus mutans insaliva with monoclonal antibodies developed targeting Ag I/II and glucosyltransferases (gtf B, gtf C and gtf D) inStreptococcus mutans. In the three groups tested (adults, minors, and minors under orthodontic treatment), theresults of the DMFT scores, the colony density (CFU/mL) in their saliva was measured using Dentocult-SMstrip mutans, polymerase chain reaction was performed to test whether Streptococcus mutans and Streptococcussobrinus were present, and Streptococcus mutans detecting tests performed in their saliva using four types ofmonoclonal antibody were collected. In conclusion, it was demonstrated that the Streptococcus mutants plays more important role in forming dentalcaries compared to Streptococcus sobrinus, and that the monoclonal antibodies against glucosyltransferases(gtf B, gtf C, gtf D) and Ag I/II of Streptococcus mutans are superior in detecting Streptococcus mutans toDentocult-SM strip mutans or polymerase chain reaction.

KEYWORDS

Monoclonal antibody, Streptococcus mutans, Glucosyltransferase B, C, D, Ag I/II

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* References for papers published after 2023 are currently being built.

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Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

Detection of Streptococcus mutans in Saliva using Monoclonal Antibodies

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* References for papers published after 2023 are currently being built.

Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

Detection of Streptococcus mutans in Saliva using Monoclonal Antibodies

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KEYWORDS

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