Oral Complications after Antineoplastic Treatment in Pediatric Patients (소아환자의 항암치료 후 나타나는 구강 내 합병증)

Yongjin Lee (이용진); Jaehwan Kim (김재환); Choi Nam-Ki (최남기); Kim Seon Mi (김선미)

doi:10.5933/JKAPD.2019.46.3.239

Oral Complications after Antineoplastic Treatment in Pediatric Patients

Journal of the Korean academy of pediatric dentistry
Abbr : J Korean Acad Pediatr Dent
2019, 46(3), pp.239-246
DOI : 10.5933/JKAPD.2019.46.3.239
Publisher : The Korean Academy Of Pediatric Dentistry
Research Area : Medicine and Pharmacy > Dentistry
Received : November 21, 2018
Accepted : December 11, 2018
Published : August 31, 2019

Yongjin Lee ¹, Jaehwan Kim ², Choi Nam-Ki ³, Kim Seon Mi ³

¹전남대학교 치의학전문대학원 소아치과학교실
²전남대학교병원
³전남대학교

Accredited

ABSTRACT

The purpose of this study was to examine dental complications and to evaluate the effects of initial treatment age, treatment modalities, and treatment duration on the disorder after radiation and chemotherapy in pediatric cancer patients. For 93 children with clinical and radiographic data, the number of teeth, the morphology of teeth, the shape of the roots, and development status of the dentition were evaluated. Dental development disorders were found in 61.3% of the children. The mostly found abnormality was root deformity with the prevalence of 31.2%. In children submitted to the therapy before the age of 6, the number of missing teeth (p = 0.029) and microdontia (p = 0.003) were greater compared to the children who started to receive the treatment after the age of 6. The combination of radiation and chemotherapy showed significantly greater incidences of missing teeth (p = 0.030), microdontia (p = 0.046), and root deformity (p = 0.009) when compared with the sole application of chemotherapy. When the children were submitted to anticancer therapy for 18 months or longer duration, greater number of missing teeth (p = 0.032), microdontia (p = 0.011), root deformity (p = 0.025), and total number of teeth affected (p = 0.036) were observed compared with duration less than 18 months. The number of dental abnormalities increased when the children were treated at earlier ages, with combination of radiation and chemotherapy, and for longer period of time.

KEYWORDS

Pediatric cancer, Radiation, Chemotherapy, Dental abnormality, Developmental disorder

Citation status

* References for papers published after 2023 are currently being built.

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Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

Oral Complications after Antineoplastic Treatment in Pediatric Patients

ABSTRACT

KEYWORDS

Citation status

* References for papers published after 2023 are currently being built.

Journal of the Korean academy of pediatric dentistry 2023 KCI Impact Factor : 0.48

Oral Complications after Antineoplastic Treatment in Pediatric Patients

ABSTRACT

KEYWORDS

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