Fe-doped beta-tricalcium phosphate; crystal structure and biodegradable behavior with various heating temperature (Fe 이온 치환 beta-tricalcium phosphate의 하소 온도에 따른 미세구조 및 분해 특성)

YOOKYUNGHYEON (유경현); Hyeon Jin Kim (김현진); Sun， woogyeong (선우경); Seog-Young Yoon (윤석영)

doi:10.6111/JKCGCT.2020.30.6.244

Fe-doped beta-tricalcium phosphate; crystal structure and biodegradable behavior with various heating temperature

Journal of the Korean Crystal Growth and Crystal Technology
Abbr : J. Korean Cryst. Growth Cryst. Technol.
2020, 30(6), pp.244-250
DOI : 10.6111/JKCGCT.2020.30.6.244
Publisher : The Korea Association Of Crystal Growth, Inc.
Research Area : Engineering > Materials Science and Engineering
Received : November 23, 2020
Accepted : November 26, 2020
Published : December 31, 2020

YOOKYUNGHYEON ¹, Hyeon Jin Kim ¹, Sun， woogyeong ¹, Seog-Young Yoon ¹

¹부산대학교

Accredited

ABSTRACT

β-Tricalcium phosphate (β-TCP, Ca3(PO4)2) is a kind of biodegradable calcium phosphate ceramics with chemicaland mineral compositions similar to those of bone. It is a potential candidate for bone repair surgery. To improve thebioactivity and osteoinductivity of β-TCP, various ions doped calcium phosphate have been studied. Among them, Iron is atrace element and its deficiency in the human body causes various problems. In this study, we investigated the effect of Feions on the structural variation, degradation behavior of β-TCP. Fe-doped β-TCP powders were synthesized by the coprecipitationmethod, and the heat treatment temperature was set at 925 and 1100℃. The structural analysis was carried out by Rietveld refinement using the X-ray diffraction results. Fe ions existed in a different state (Fe2+ or Fe3+) with different heat treatment temperatures, and the substitution sites (Ca-(4) and Ca-(5)) also changed with temperature. The degradation rate was fastest at Fe-doped β-TCP with heated at 1100℃. The cell viability behavior was also enhanced with the substitution of Fe ions. Therefore, the substitution of Fe ion has accelerated the degradation of β-TCP and improved the biocompatibility. It could be more utilized in biomedical devices.

KEYWORDS

Tricalcium phosphate, Fe ion substitution, Crystal structure, Rietveld refinement, Degradation behavior

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Journal of the Korean Crystal Growth and Crystal Technology 2023 KCI Impact Factor : 0.19

Fe-doped beta-tricalcium phosphate; crystal structure and biodegradable behavior with various heating temperature

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Journal of the Korean Crystal Growth and Crystal Technology 2023 KCI Impact Factor : 0.19

Fe-doped beta-tricalcium phosphate; crystal structure and biodegradable behavior with various heating temperature

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