@article{ART003152917},
author={Jiyu Lee and Juyoung Lee and Kyung-Hyeon Yoo and Seog-Young Yoon},
title={Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells},
journal={Journal of the Korean Crystal Growth and Crystal Technology},
issn={1225-1429},
year={2024},
volume={34},
number={6},
pages={259-266},
doi={10.6111/JKCGCT.2024.34.6.259}
TY - JOUR
AU - Jiyu Lee
AU - Juyoung Lee
AU - Kyung-Hyeon Yoo
AU - Seog-Young Yoon
TI - Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells
JO - Journal of the Korean Crystal Growth and Crystal Technology
PY - 2024
VL - 34
IS - 6
PB - The Korea Association Of Crystal Growth, Inc.
SP - 259
EP - 266
SN - 1225-1429
AB - The interactions of human dental pulp stem cell (hDPSCs) with Li-doped β-tricalcium phosphates (β-TCP) and their degradation behavior in biological environment were investigated. For this purpose, three different amounts of Li ions- doped β-TCP were synthesized by co-precipitation method. The lattice constants of crystal structure were slightly changed with addition of lithium due to the replacing site and the difference of ionic radius. Li-doped β-TCP showed significantly higher ALP activity compared to pure β-TCP, suggesting that lithium ion positively effects the cell differentiation. In addition, the osteogenic performance was also improved by the adding Li ions. These could demonstrate the benefit of incorporating an important trace elements, lithium, into β-TCP to achieve better osteogenesis activity. As a result, the combination of Li with β-TCP may be a promising method to improve bone regeneration, suggesting excellent in vitro osteogenic stimulation properties by inducing bone related gene expression in hDPSCs.
KW - β-Tricalcium phosphate;Lithium;Lattice parameters;Dental pulp stem cell
DO - 10.6111/JKCGCT.2024.34.6.259
ER -
Jiyu Lee, Juyoung Lee, Kyung-Hyeon Yoo and Seog-Young Yoon. (2024). Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells. Journal of the Korean Crystal Growth and Crystal Technology, 34(6), 259-266.
Jiyu Lee, Juyoung Lee, Kyung-Hyeon Yoo and Seog-Young Yoon. 2024, "Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells", Journal of the Korean Crystal Growth and Crystal Technology, vol.34, no.6 pp.259-266. Available from: doi:10.6111/JKCGCT.2024.34.6.259
Jiyu Lee, Juyoung Lee, Kyung-Hyeon Yoo, Seog-Young Yoon "Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells" Journal of the Korean Crystal Growth and Crystal Technology 34.6 pp.259-266 (2024) : 259.
Jiyu Lee, Juyoung Lee, Kyung-Hyeon Yoo, Seog-Young Yoon. Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells. 2024; 34(6), 259-266. Available from: doi:10.6111/JKCGCT.2024.34.6.259
Jiyu Lee, Juyoung Lee, Kyung-Hyeon Yoo and Seog-Young Yoon. "Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells" Journal of the Korean Crystal Growth and Crystal Technology 34, no.6 (2024) : 259-266.doi: 10.6111/JKCGCT.2024.34.6.259
Jiyu Lee; Juyoung Lee; Kyung-Hyeon Yoo; Seog-Young Yoon. Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells. Journal of the Korean Crystal Growth and Crystal Technology, 34(6), 259-266. doi: 10.6111/JKCGCT.2024.34.6.259
Jiyu Lee; Juyoung Lee; Kyung-Hyeon Yoo; Seog-Young Yoon. Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells. Journal of the Korean Crystal Growth and Crystal Technology. 2024; 34(6) 259-266. doi: 10.6111/JKCGCT.2024.34.6.259
Jiyu Lee, Juyoung Lee, Kyung-Hyeon Yoo, Seog-Young Yoon. Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells. 2024; 34(6), 259-266. Available from: doi:10.6111/JKCGCT.2024.34.6.259
Jiyu Lee, Juyoung Lee, Kyung-Hyeon Yoo and Seog-Young Yoon. "Synthesis and characterization of Li-doped tricalcium phosphate for improving the differentiation of human dental pulp stem cells" Journal of the Korean Crystal Growth and Crystal Technology 34, no.6 (2024) : 259-266.doi: 10.6111/JKCGCT.2024.34.6.259
