2013, Vol.23, No.4

A Retrospective Study on the Effects of ShinBaro Pharmacopuncture and Jungsongouhyul Pharmacopuncture on Whiplash Injury by Traffic Accident

김태헌 , 박원형 , Cha Yun Yeop | 2013, 23(4) | pp.1~7 | number of Cited : 17

Effects of Jengjengamiyijin-tang (zhèngzhuànjiāwèièrchéntāng) on Lowering Lipid, Antioxidation and Production of Inflammatory Mediators Being Used Rats Fed on High Oxidized Fat

허성규 , 박원형 , Cha Yun Yeop | 2013, 23(4) | pp.9~21 | number of Cited : 2

Objectives The purpose of this study was investigating effects of Jengjengamiyijin-tang(zhèngzhuànjiāwèièrchéntāng) (JGYT) on lowering lipid, antioxidation and production of inflammatorymediators being used rats fed on high oxidized fat. Methods We divided fat Sprague-Dawley rats fed on high oxidized into 4 groups. Eachof 8 rats was divided into a control group and experimental groups. We fed a control groupof rats a basal diet and administered normal saline (100 mg/kg, 1 time/1 day) for 4 weeks. And We fed each experimental group of rats basal diet and administered an extract ofJGYT extracts (100 mg/kg, 200 mg/kg, 300 mg/kg, 1 time/1 day) for 4 weeks. At the endof the experiment, the rats were sacrificed to determine their chemical composition. Wemeasured lipid of plasma and liver, concentration of proinflammatory cytokines, antioxidativeactivity and plasma tumor necrosis factor-α (TNF-α), plasma interleukin-6 (IL-6),Apo-B, Apo-E and Leptin gene expression. Results 1. Concentration of plasma FFA, LDL-cholesterol, plasma and liver total cholesterolshowed a significant decrement in JGYT groups. However, concentration of plasmaHDL-cholesterol showed a significant increment in JGYT groups. 2. Concentration of plasmaand liver TG, TBARS showed a significant decrement in JGYT groups. However, concentrationof liver GSH-Px, SOD and CAT showed a significant increment in JGYT groups. 3. Plasma GPT activity and concentration of plasma IL-6, TNF-α, NO, Ceruloplasmin, α1-acid glycoprotein showed a significant decrement in JGYT groups. 4. In the analysis ofRT-PCR, gene expression of Apo-B and Apo-E in the JGYT groups showed a low expressionthan that of control group. However, the gene expression of leptin showed no differencein all the treatment groups. 5. The ratio of leptin expression per β-actin expressionshowed no significant difference among all treatment groups. However, The ratio of Apo-Band Apo-E expression per β-actin expression showed a significant decrement in JGYTgroups. Conclusions According to this study, extract of JGYT showed a positive effect in loweringlipid, antioxidation and control of inflammatory mediators production.

Effects of Saengkanggamchotang (SKT) on MIA-Induced Osteoarthritis in Rats

최보미 , Minseok Oh | 2013, 23(4) | pp.23~37 | number of Cited : 2

Objectives This study was performed to investigate the effects of Saengkanggamchotang(SKT) on the monosodium iodoacetate (MIA) induced osteoarthritis in rats. Methods Osteoarthritis was induced by injection of MIA (50 ul, 60 mg/ml) into kneejoints of rats. Rats are divided into a total of 4 groups (normal, control, positive comparisongroup, SKT treated group, each n=6). Normal group are not treated at all without inducingosteoarthritis whereas control group were induced for osteoarthritis by MIA and oral medicatedwith 20 ml of distilled water per day. Positive comparison group was injected withMIA and after 7 days, that was taken indomethacin (30 mg/kg/mouse). SKT treated groupwas injected with MIA and after 7 days that was taken SKT (30 mg/kg/mouse). Positivecomparison group and SKT treated group were oral medicated for each substance a totalof 4 weeks with one time per day. After experiments (from 1 week after injection of papainto 4 weeks elapsed), the functions of liver and kidney, Prostaglandin E2, inflammatory cytokine(IL-1β, IL-6, TNF-α), osteocalcin, TIMP-1, MMP-9 within serum. Knee joint structureswere observed by H&E, safranin-O staining method, and amount of cartilage weremeasured by μCT-arthrography. Results 1) Hind paw weight bearing ability was significantly improved. 2) Functions of liverand kidney were not affected. 3) Prostaglandin E2, osteocalcin, TIMP-1, MMP-9 in serumwere significantly decreased. 4) Inflammatory cytokine IL-1β was significantly decreased,and IL-6, TNF-α were decreased but had not significant. 5) In terms of histopathology,significantly reduced subsidence of cartilage and bone in H&E staining. And inSafranin O staining, proteoglycan content in synovial membrane was significantly increasedcompared with control group. 6) Destruction of cartilage on μCT-arthrographywas significantly reduced. Conclusions Based on all results mentioned above, Saengkanggamchotang (SKT) isbelieved to be meaningful for suppressing the progress of osteoarthritis and its treatments.

Effect of Kyejakjimo-tangkami (Guìsháozhīmǔ-tāngjiāwèi) on Osteoarthritis

홍성민 , Minseok Oh | 2013, 23(4) | pp.39~57 | number of Cited : 2

Objectives The purpose of this study is to prove the effect of Kyejakjimotangkami(KMK)on osteoarthritis. Methods We checked antioxidant activity and measured production of IL-1β, IL-6,TNF-α in RAW 264.7 cell after treat by KMK. Then we measured hind paw weight ofWister Rat with arthritis induced by MIA after KMK oral administration, checkedProstaglandin E2, IL-1β, IL-6, TNF-α, Osteocalcin, TIMP-1, MMP-9, LTB-4 in serum,ran histopathological test and μCT-arthrography. Results 1. DPPH radical Scavenging was increased depend on concentration of KMKethanol extract in RAW 264.7 cell. 2. Production of NO was significantly decreased byKMK ethanol extract on concentration of 200μg/ml in RAW 264.7 cell. 3. Production ofIL-1β was significantly decreased by KMK ethanol extract on concentration of 200μg/ml. And Production of IL-6 ,TNF-α were significantly decreased KMK ethanol extract ofevery concentration in RAW 264.7 cell. 4. Result of checking hind paw weight when administeredKMK ethanol extract to Wister Rat with arthritis induced by MIA was significantlyhigher than control group and similar to normal group. 5. Production ofProstaglandin E2, IL-1β, Osteocalcin, TIMP-1, MMP-9 and LTB-4 in serum was significantlydecreased by KMK ethanol extract after administerd to Wister Rat with arthritisinduced by MIA. 6. In Hematoxylin & Eosin staining and Safranin-O staining, we could findinflammation of synovial cell, infiltration of macrophage and granulocyte and degenerationof cartilage and bone were decreased in comparison with control group. 7. When checkedcartilage volume to examine degree of cartilage degeneration using μCT-arthrography,volume of cartilage was increased in comparison with control group. Conclusions Comparison of the results for this study showed that KMK ethanol extracthave anti-inflammatory effectiveness and can protect cartilage and bone. So we expectthat KMK can be used as a effective drugs for osteoarthritis.

Systematic Review of High Frequency of Acupuncture Point and Self Exercise Therapy for Lower Back Pain

남대진 , 허건 , 이형은 and 4 other persons | 2013, 23(4) | pp.59~71 | number of Cited : 6

Narrative Review of Clinical Trial on Scolopendrid Pharmacopuncture in Korean Literature

조동찬 , 이진현 , 김창곤 and 4 other persons | 2013, 23(4) | pp.73~82 | number of Cited : 7

Objectives The purpose of this review is to investigate studies of Scolopendrid pharmacopunctureand the evidence of it’s effects in order to suggest a better research method inthe future. Methods We retrieved numbers of clinical studies about Scolopendrid pharmacopuncturefrom 7 Korean web databases, using key words such as ‘Scolopendrid’, ‘ScolopendridAND Pharmacopuncture’. This study had been conducted from 1st May 2013 to31th July 2013. Controlled studies and case studies were only used for this study. Clinicalstudies that we picked from the databases were classified according to the diseases thatthose studies are about, and from these clinical studies, we are to research what has to beimproved generally in clinical researches. Results 18 case studies, 4 controlled studies had been under research. Scolopendridpharmacopuncture has a therapeutic effect mainly in musculoskeletal and neurological diseasessuch as herniated intervertebral disc, carpal tunnel syndrome, swollen leg, feeling ofcold on legs, wrist ganglion, lateral epicondylitis, radial nerve palsy, cervical myelopathy,cauda equina syndrome, postauricular pain; as an early symptom of Bell’s palsy, pain ofpopliteal part, gout, plantar fasciitis, cellulitis, frozen shoulder, pain of hip adductors. However objectivity and reliability of the Scolopendrid pharmacopuncture studies still remainscontroversial. Conclusions It has been suggested that there are positive effects of Scolopendrid pharmacopuncturetherapy in treating specific diseases (especially neuromusculoskeletal diseases). However, this narrative review can’t conclude and prove that the Scolopendridpharmacopuncture has positive effectiveness on these diseases unlike systematic review. So, in order to put Scolopendrid pharmacopuncture therapy to use for many kinds of diseasesin more reasonable ways, it is essential to build well-designed clinical research tools. In the future, abundant case studies, more follow-up trials and randomized controlled trialsbased on the korean medicine should be done to use Scolopendrid pharmacopuncture fora clinical purpose.

A Review of Studies Comparing of Surface Electromyography Values between the Low-back Pain Group and Healthy Controls

유덕주 , 조재홍 , Chung, Seok Hee | 2013, 23(4) | pp.83~93 | number of Cited : 2

A Review of Questionnaire for the Clinical Trials on Chronic Low Back Pain

김두희 , 신우석 , 이진원 and 12 other persons | 2013, 23(4) | pp.95~115 | number of Cited : 11

Research Trends of Abnormal Postures in Korean Literature -Based on Abnormal Spinal Alignment in the Sagittal Plane-

박정식 , Lim Hyung Ho , SONG YUN KYUNG and 9 other persons | 2013, 23(4) | pp.117~128 | number of Cited : 6

A Review of Recent Clinical Studies for Manual Therapy on Temporomandibular Joint Disorder

노해린 , 김민영 , 박소현 and 3 other persons | 2013, 23(4) | pp.129~141 | number of Cited : 4

Development of Questionnaire for Pattern Identification of Chronic Low Back Pain by Delphi Method

Min-Youn Ahn , SONG YUN KYUNG , KO SEONG-GYU and 1 other persons | 2013, 23(4) | pp.143~158 | number of Cited : 7

A Study on the Characteristics of Lumbar Disc Herniation Being Classified Blood Stasis and Phlegm-Retained Fluid

엄태웅 , 이차로 , Hojun Kim and 1 other persons | 2013, 23(4) | pp.159~167 | number of Cited : 1

A Study on Relationship between Lumbosacral Curvature and Neck-Waist Circumference on College Students in Seoul

양요찬 , 송은모 , Kim Koh-Woon and 2 other persons | 2013, 23(4) | pp.169~176 | number of Cited : 3

Cross-sectional Study of Therapy Type and Pattern Identification in Lumbago Patients

Go, Ho Yeon , Ko YounSeok , Lee Jung-han and 9 other persons | 2013, 23(4) | pp.177~184 | number of Cited : 8

Efficacy and Safety of Micro Current Tape on Chronic Low Back Pain:One Group Pre-Post Test Design, Multi Center Pilot Study

박현건 , 김종연 , 이운섭 and 4 other persons | 2013, 23(4) | pp.185~194 | number of Cited : 1

The Study on Correlation between the Forward Head Posture and Spinal Alignment

정현우 , 신우석 , 김두희 and 12 other persons | 2013, 23(4) | pp.195~202 | number of Cited : 22

The Correlation Analysis of Low Back Pain, Stress by Event, and Fear-Avoidance Beliefs Caused by Traffic Accidents

최희승 , 김민영 , 김진수 and 5 other persons | 2013, 23(4) | pp.203~212 | number of Cited : 2

A Descriptive Statistical Analysis of the Hospitalized Patients with Low Back Pain in Departments of Korean Rehabilitation Medicine of Korean Medicine Hospitals

맹태호 , 김종연 , 이운섭 and 11 other persons | 2013, 23(4) | pp.213~223 | number of Cited : 4

Objectives Low back pain (LBP) is one of the most common reason for people in Koreato visit Korean medical institutions. To assess actual amounts of use in the treatment ofLBP in Korean medicine and to provide objective base line data for policy decision making,research regarding the current state of LBP patients' treatment in Korean medical institutionsare in need. Methods The current study was designed as a retrospective chart review to investigatedescriptive characteristics of LBP patients. The clinical records of 304 patients who werehospitalized for the treatment of LBP in Korean rehabilitation medicine inpatient clinics offive different Korean medicine hospitals were analyzed. The percentage of patient characteristicssuch as sex, age, average duration of admission, insurance type, diagnosed LBPrelated disease code, and rates of interventions applied were assessed. Results 1. The female sex was significantly predominant among patients with LBP : 105patients (34.5%) were male and 199 patients (65.5%) were female. Percentage of the patients'age appeared as followed : 76 people (25.0%) were in their 50s, 64 people (21.1%)were in their 40s, 51 people (16.8%) were in their 30s, 37 people (12.2%) were in their 60s,and 33 people (10.9%) were in their 70s. Approximately half of the total LBP patients investigatedwere older than 50. 2. The average duration of admission was 16.2 days. Approximately one third (30.3%) of the patients were hospitalized for 8 to 14 days. 3. Female patients tended to stay admitted in hospitals slightly longer than male patients. Elderly (age 60~79) patients stayed in hospitals longer (17.8 days) compared to younger(age 20~39) patients (13.5 days). 4. More than half of the patients (171 cases, 56.3%) hadtheir hospital bills covered with automobile insurance. 40.1% (122 cases) of the patientshad medical insurance to cover their hospital bills. The average duration of admission ofpatients who had automobile insurance was 14.2 days, while that of the patients who hadmedical insurance was 18.4 days. 5. "Sprain and strain of the lumbar spine and pelvis"was the most commonly used (195 cases, 64.1%) disease code in patients with LBP. Patients diagnosed as "lumbar and other intervertebral disc disorders with radiculopathy"required the longest admission duration (22.1 days). 6. Herbal medication was applied toall of the patients during admission. Acupuncture was applied to all of the patients exceptone case diagnosed as spinal stenosis. Physical therapy, cupping therapy, moxibustiontherapy, chuna therapy, and pharmacopuncture therapy were applied to 94.7, 92.8, 85.2,83.9, and 49.7% of the patients, respectively. 7. There were certain differences amongKorean medicine hospitals in terms of the LBP patients' duration of admission, type of insurance,frequency of the disease code use, type of intervention applied. Conclusions It is thought that the current study can be used as reference data in assessingthe current state of LBP treatment in Korean rehabilitation medicine and a basisfor future research. Provided improvements of certain limitations of the current study in futureresearches, such data would act as better base line data in policy decision making.

A Retrospective Study of Acute Lumbar Sprain Patients on the Effect of Korean Medicine Treatment with Dokhwal-tang (Duhuo-tang)

정해창 , 박동수 , Jeong， Su-hyeon | 2013, 23(4) | pp.225~231 | number of Cited : 0

The Retrospective Analysis of 1,162 Traffic Accident Inpatients in Korean Medicine Hospital

신재화 , Minseok Oh | 2013, 23(4) | pp.233~250 | number of Cited : 25

Objectives The purpose of this study was to investigate the characteristics of inpatientswho were admitted to Korean medicine hospital due to traffic accident. Methods 1,162 traffic accident patients who were admitted to department of KoreanRehabilitation Medicine of Cheonan Korean Medicine Hospital, Dae-Jeon University from 1st,January, 2011 to 31th, December, 2012 were analyzed according to the medical charts. Results 1. The average treatment result was 3.22 and in most (71.52%) of the patients,symptoms were more than improved. 2. In distribution according to age and sex, peoplein their 30s numbered the most both in male (12.65%) and female (14.72%). The 1,162 inpatientscomprised of 457 (39.33%) male and 705 (60.67%) female. 3. 541 (46.56%) patientsadmitted in 2011 and 621 (53.44%) patients admitted in 2012. 4. 695 (59.81%) patientsvisited Cheonan Korean Medicine Hospital within 0~2 days after their traffic accident,followed by 242 (20.83%) patients who visited within 3~5 days after their trafficaccident. Patients who admitted earlier showed more improvement in symptoms. 5. Theaverage admission days were 9.32 days. Most (57.66%) patients discharged within 1week. 6. 825 (71.00%) patients were driving sedan at the time of accident, followed by105 (9.04%) SUV owners and 71 (6.11%) pedestrians. 7. Rear-end collision accidentnumbered the most (45.61%), followed by lateral collision (24.35%) and frontal collision(14.72%). 8. Most frequently prescribed examination was X-ray (95.52%), followed by CT(8.69%) and MRI (3.01%). 9. Most frequently given diagnosis was sprain (1,126 (96.90%)patients), followed by concussion & abrasion (178 (15.32%) patients) and fracture (109(9.38%) patients). 10. Most frequently given Korean medicine treatment was acupuncture(1,162 (100%) patients), followed by anti-inflammatory pharmacopuncture (652 (56.11%)patients) and moxibustion (462 (39.76%) patients). 11. Most frequently given Korean medicinephysiotherapy was infra-red (1,161 (99.91%) patients), followed by cupping therapy(1,152 (99.14%) patients) and hotpack (1,137 (97.85%) patients). 12. Most frequently prescribedherb medicine was huishou-san (13.51%), followed by dangguixu-san (12.65%)and yaojiao-tang G (7.06%)Conclusions In this study, people in their 30s, females, within 0~2 days since the accidenttook the highest percentage from each category of patients who admitted to KoreanMedicine Hospital due to traffic accident. Patients who admitted earlier showed more improvementin symptoms and also discharged earlier.

A Case Report of Patient with Recurrent Patellar Dislocation Treated by Korean Medicine Treatment in Combination with Intra-articular Bee Venom Injection and Needle-embedding Therapy

유경곤 , 김진희 , 민선정 and 3 other persons | 2013, 23(4) | pp.251~259 | number of Cited : 5

A Case Report of the Korean Medical Treatment for Patulous Eustachian Tube Patient with Headache

김진희 , 민선정 , 유경곤 and 2 other persons | 2013, 23(4) | pp.261~268 | number of Cited : 2

KJCKorea
Journal Central

Journal of Korean Medicine Rehabilitation 2023 KCI Impact Factor : 0.6

2013, Vol.23, No.4