2014, Vol.24, No.4

Study of Mori Fructus and Dried Mori Fructus Extracts on the Antioxidant Effect and the Inhibitory Effect on Adipocyte Differentiation

김형구 , Jing-Hua Wang , Lim Dongwoo and 4 other persons | 2014, 24(4) | pp.1~13 | number of Cited : 0

Study on Antioxidant and Anti-inflammatory Effects of Components of Mahwangbujaseshin-tang

최철우 , Minseok Oh | 2014, 24(4) | pp.15~28 | number of Cited : 4

Objectives This study was carried out to find out the Antioxidant and Anti-inflammatory Effects of Components of Mahwangbujaseshin-tang in LPS-Stimulated RAW264.7 Macrophages. Methods There are 5 experimental groups. ; normal, control, EH (Ephedrae Herba), ALRP (Aconiti Lateralis Radix Preparata) and AR (Asiasari Radix). The extract of EH, ALRP and AR (100 μg/ml) was added to each group. We examined cytotoxicity, total phenolic contents, DPPH and ABTS free radical scavenging activity, Intracellular ROS (reactive oxygen species) production, NO (Total Nitric oxide), iNOS (inducible nitric oxide synthase), PGE2 (prostaglandin E2), COX-2 (cyclooxygenase-2), IL-1β (interleukin-1β), IL-6 (interleukin- 6), TNF-α (tumor necrosis factor-α), MMP-9 (matrix metalloproteinase-9), TIMP-1 (tissue inhibitor of metalloproteinase-1) and HO-1 (heme oxygenase-1) expression level. Results 1. Total phenolic contents of EH were in the highest level. 2. DPPH and ABTS free radical scavenging activity of EH was in the highest level. 3. ROS production was significantly decreased in AR. 4. NO production was significantly decreased in EH, ALRP, AR and iNOS expression was decreased in EH, AR. 5. PGE2 and COX-2 expression was decreased in EH, AR. 6. IL-1β production was significantly decreased in EH, AR and IL-6 production was significantly decreased in AR. TNF-α production was significantly decreased in ALRP, AR. 7. MMP-9 and TIMP-1 production were significantly decreased in EH. 8. HO-1 expression was significantly increased in EH. 9. With simultaneous usage of SnPP which is expression inhibitor of HO-1, NO, IL-1β, IL-6 and TNF-α production were partially increased in EH, ALRP, AR. Conclusions According to this study, Components of Mahwangbujaseshin-tang have anti-oxidants and anti-inflammation effects in LPS-Stimulated RAW264.7 Macrophages.

Tendency of Korean Herbal Medicine Prescriptions Used for Dementiain Korean Experimental Researches−Mainly about Domestic Dissertations for a Degree−

Jo Hee Geun , Hwi-joong Kang , 고용준 and 7 other persons | 2014, 24(4) | pp.29~40 | number of Cited : 5

The Domestic Trend of Failed Back Surgery Syndrome: Definition, Treatment Trials and Instruments for Assessment

최희승 , Cha Yun Yeop , 박원형 and 6 other persons | 2014, 24(4) | pp.41~48 | number of Cited : 6

The Research Trends on the Acupuncture Treatment of Lumbar Herniated Intervertebral Disc Using PubMed Database

신우석 , 박원형 , Cha Yun Yeop | 2014, 24(4) | pp.49~60 | number of Cited : 12

Objectives The purpose of this study is to research current trends of acupuncture treatment of lumbar herniated intervertebral disc using the PubMed database. Methods We set up the search strategy and investigated clinical trials on acupuncture treatment of lumbar herniated intervertebral disc through PubMed search. This study analyzed previous researched papers published from January 1st, 2000 to April 30th, 2014, and classified them by publication year, journal names, types of literature, treatment methods and evaluation scales. To assess the quality of the reviewed literature, randomized controlled trial (RCT) studies were assessed by Cochrane's risk of bias (ROB) tool and non-RCT studies were assessed by risk of bias for non-randomized studies (RoBANS). Results We found 35 studies on the acupuncture treatment of lumbar herniated intervertebral disc. Papers on this topic have been published, on average, three to four times annually in 9 journals since the mid-2000's. The journal with the largest number of publications was Chinese Acupuncture & Moxibustion, and most of articles were classified as RCT. Acupuncture treatment was performed individually or together with other treatments. The most frequently used pain evaluation index was visual analogue scale (VAS). The index of effective rate was used frequently but there was a lack of objectivity. In regards to the quality of the studies, outcome assessment in RCT showed that random sequence generation, allocation concealment, and the blinding of participants and personnel increase potential of risk of bias. For non-RCT assessment, outcome showed that confounding variable, measurement of intervention were at high risk of bias. Conclusions In order to obtain objective clinical evidence of acupuncture treatment of lumbar herniated intervertebral disc, further clinical studies should be designed to minimize the risk of bias, using STRICTA with larger sample sizes.

The Characteristics in Obesity Classification Group of College Student by Analyzing Their BMI and Blood Test and the Association between Factors Contributing to Obesity and Obesity according to BMI

박정식 , 이중재 , Oh, Hyun Sook and 1 other persons | 2014, 24(4) | pp.61~70 | number of Cited : 0

Effect of BMI, Blood Parameters and Life Pattern on KOQOL in Health Checkup Examinees of College Students

안민윤 , 이중재 , Oh, Hyun Sook and 1 other persons | 2014, 24(4) | pp.71~82 | number of Cited : 6

Classification of Muscles into Meridian Sinew: A Literature Review

문수정 , 김성하 , 이상훈 | 2014, 24(4) | pp.83~96 | number of Cited : 3

Reporting of Adverse Events in Randomized Controlled Trials of Bee Venom Acupuncture: A Systematic Review

이운섭 , Kim Sung-Soo | 2014, 24(4) | pp.97~109 | number of Cited : 2

Reviewing Research of Korean Medical Treatment of Wrist Ganglion

원제훈 , Young Jun Kim , Hee Duk An and 1 other persons | 2014, 24(4) | pp.111~116 | number of Cited : 2

Analysis of the Relationship between Hip Internal Rotation Angle and the Site of Herniation of Single Level Lumbar Intervertebral Disc Using Logistic Regression

김신웅 , 남항우 , 김세준 and 9 other persons | 2014, 24(4) | pp.117~127 | number of Cited : 1

A Study for Clinical and Radiological Correlation between Lumbar Lordotic Angle, Lumbar Intervertebral Disc Angle and Lumbar Spinal Stenosis

김종수 , 손슬기 , 김세준 and 5 other persons | 2014, 24(4) | pp.129~136 | number of Cited : 4

The Study on History Period and Treatment Outcomes of Patients Admitted to a Korean Medicine Hospital for Low Back Pain

조창영 , 김원우 , 성익현 and 5 other persons | 2014, 24(4) | pp.137~143 | number of Cited : 0

The Comparative Study on the Effect of HWANGRYUNHAEDOKTANG Pharmacopuncture and Essential Bee Venom Pharmacopuncture for Cervical Pain Caused by Traffic Accidents: A Randomized Controlled Trial

이옥진 , 남대진 , 허건 and 6 other persons | 2014, 24(4) | pp.145~153 | number of Cited : 16

Predicting the Concentration of Obesity-related Metabolites via Heart Rate Variability for Korean Premenopausal Obese Women: Multiple Regression Analysis

김종연 , 양요찬 , 이운섭 and 7 other persons | 2014, 24(4) | pp.155~162 | number of Cited : 1

Objectives Advanced researches on the relationship between obesity and heart rate variability (HRV), heretofore, focused on characteristics of HRV depending on the state of obesity. However, the previous researches have not quantified predictive power of HRV toward the obesity-related variables, which is rather more meaningful for clinicians who regularly treat obese patients. Hence, we designed a research to investigate whether HRV could predict serum levels of obesity-related metabolites. Methods Ninety obese premenopausal women meeting the inclusion criteria were recruited. The HRV test, blood sampling, and measurement of physical traits were conducted. Multiple regression analysis of the measurement data was carried out, putting obesity-related metabolites (insulin, glucose, triglyceride, hs-CRP, HDL, LDL, total cholesterol) as outcome variables and the others as predictors. To select appropriate predictive variables, the Akaike's Information Criterion (AIC) was applied. Normality and homoskedasticity of residuals for each model were tested to identify if there were any violations of the regression analysis's basic assumption. Logarithm transformation was used for the values of the concentration of metabolites and the HRV. Results The regression model including Total Power (TP) value and BMI had significant predictive power for serum insulin concentration (F(2, 88)=835.7, p＜0.001, R2=0.95). The regression coefficient of ln (TP) was -0.1002. However, it was not sure if the HRV could predict concentrations of other metabolites. Conclusions The results suggest that the Total Power (TP) value of the HRV can predict the level of serum insulin. If the BMI could be assumed as being constant, when the TP value is multiplied by n, the predicted change of insulin could be drawn by multiplying n−0.1002. The uncertainty of this model can be assumed as approximately 5%.

Correlations of Forward Head Posture to Heart Rate Variability and Standing Posture Balance Factors

기성훈 , SONG YUN KYUNG | 2014, 24(4) | pp.163~176 | number of Cited : 6

Correlation Analysis of Body Parameters between Chuna Posture Analysis System and X-ray

김창곤 , 이진현 , 민선정 and 5 other persons | 2014, 24(4) | pp.177~185 | number of Cited : 4

Systematic Review of External Qigong Therapy for Joint Pain

이현엽 , Hwang Mansuk , Heo, In and 3 other persons | 2014, 24(4) | pp.187~193 | number of Cited : 2

One Case Report on Physical Sequelas after Spinal Epidural Abscess Surgery

권정국 , 이종하 , Keum Dong-ho | 2014, 24(4) | pp.195~201 | number of Cited : 1

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Journal Central

Journal of Korean Medicine Rehabilitation 2023 KCI Impact Factor : 0.6

2014, Vol.24, No.4