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The Effect of Chongbaek-san(Congbai-san) on the Body Weight and the Histological Changes in Peri-Epididymal Fat, the Biochemical Changes of Blood Serum in Obese Rats Induced by High Fat Diet

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2006, 16(3), pp.35-47
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine

노도환 1 Myeong-Jong Lee 2

1동국대학교
2강원대학교

Candidate

ABSTRACT

Objectives : This study was performed to investigate the efficiency of Chongbaek-san(Congbai-san) on the Weight changes and the histological changes in Peri-Epididymal Fat, the biochemical changes of blood serum in obese rats induced by high fat diet. Methods and Materials : Experiment animals were divided into 3 groups; normal group(normal diet, non-treated), obese group(high fat diet, non-treated) and Chongbaek-san(Congbai-san) oral feeding obese group(high fat diet, treated). Results : Chongbaek-san(Congbai-san) was investigated effects of Total Body Weight, serum Glucose and Insulin content, Total Cholesterol and Triglyceride, HDL-Cholesterol, LDL-Cholesterol content, Total Lipid and free fatty Acid content, Leptin and Uric Acid, SGOT, SGPT content, the histological changes in Peri-Epididymal in animal test. However there was no significant difference in Insulin and HDL-cholesterol. Conclusions : These results indicates that Chongbaek-san(Congbai-san) showed the treatment effects on the obesity resulted from high fat diet in rats.

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