@article{ART001179172},
author={신홍중 and Minseok Oh and Yoon il ji and 강준혁 and 최승훈},
title={The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2006},
volume={16},
number={1},
pages={93-107}
TY - JOUR
AU - 신홍중
AU - Minseok Oh
AU - Yoon il ji
AU - 강준혁
AU - 최승훈
TI - The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity
JO - Journal of Korean Medicine Rehabilitation
PY - 2006
VL - 16
IS - 1
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 93
EP - 107
SN - 1229-1854
AB - Objectives :
This experimental study was designed to investigate the effects of Soeuminbang(SEIB) on obese mice.
Methods :
In order to investigate the obese inhibitory effects of SEIB, C57BL/6 mice were induced by high fat diet. C57BL/6 mice were divided into three group(normal, high fat diet, high fat diet with SEIB extract) and fed for 13weeks. The measurements have been performed on ; the weight ; the quantity of AST, ALT, cholesterol, triglyceride, total protein, albumin ; and the quantity of obesity gene expression.
Results :
Soeuminbang(SEIB) decreased with the significance the body weight change and the final increase of body weight in obese-mouse.
SEIB decreased with the significance the weight of adipocyte in obese-mouse and also decreased the blood level of serum ALT, AST, total cholesterol, LDL-cholesterol and trigriceride, total protein and albumin in obese-mouse.
SEIB increased β3AR gene expression in primary adipocytes isolated from obese-mouse and decreased leptin expression in adipocytes tissue isolated from obese-mouse.
SEIB decreased GLUT1 and GLUT4, TNF-α expression in primary adipocytes isolated from obese-mouse.
Conclusions :
Based on these results, it is proved that SEIB is effective on obesity care and has obese-inhibitory effects in obese-mouse induced by high fat diet. So it is respected that the clinical application of SEIB can help the treatment of obesity.
KW - Soeuminbang;Obesity;Body weight;Adypocyte
DO -
UR -
ER -
신홍중, Minseok Oh, Yoon il ji, 강준혁 and 최승훈. (2006). The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity. Journal of Korean Medicine Rehabilitation, 16(1), 93-107.
신홍중, Minseok Oh, Yoon il ji, 강준혁 and 최승훈. 2006, "The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity", Journal of Korean Medicine Rehabilitation, vol.16, no.1 pp.93-107.
신홍중, Minseok Oh, Yoon il ji, 강준혁, 최승훈 "The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity" Journal of Korean Medicine Rehabilitation 16.1 pp.93-107 (2006) : 93.
신홍중, Minseok Oh, Yoon il ji, 강준혁, 최승훈. The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity. 2006; 16(1), 93-107.
신홍중, Minseok Oh, Yoon il ji, 강준혁 and 최승훈. "The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity" Journal of Korean Medicine Rehabilitation 16, no.1 (2006) : 93-107.
신홍중; Minseok Oh; Yoon il ji; 강준혁; 최승훈. The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity. Journal of Korean Medicine Rehabilitation, 16(1), 93-107.
신홍중; Minseok Oh; Yoon il ji; 강준혁; 최승훈. The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity. Journal of Korean Medicine Rehabilitation. 2006; 16(1) 93-107.
신홍중, Minseok Oh, Yoon il ji, 강준혁, 최승훈. The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity. 2006; 16(1), 93-107.
신홍중, Minseok Oh, Yoon il ji, 강준혁 and 최승훈. "The Inhibitory Effect of Soeuminbang(SEIB) on the Obesity" Journal of Korean Medicine Rehabilitation 16, no.1 (2006) : 93-107.
