@article{ART001629110},
author={Chung Won Suk and Kim Sung-Soo and oh jaekeun and LEE JUN HWAN and Kim Koh-Woon and 박현건 and 최효정 and Jongsoo Lee},
title={Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice},
journal={Journal of Korean Medicine Rehabilitation},
issn={1229-1854},
year={2012},
volume={22},
number={1},
pages={1-10}
TY - JOUR
AU - Chung Won Suk
AU - Kim Sung-Soo
AU - oh jaekeun
AU - LEE JUN HWAN
AU - Kim Koh-Woon
AU - 박현건
AU - 최효정
AU - Jongsoo Lee
TI - Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice
JO - Journal of Korean Medicine Rehabilitation
PY - 2012
VL - 22
IS - 1
PB - The Korean Academy Of Oriental Rehabilitation Medicine
SP - 1
EP - 10
SN - 1229-1854
AB - Objectives :The aim of this study was to investigate the acute toxicity and safety of fermented deer velvet antler extract in institute for cancer research(ICR) mice. Methods : To evaluate the acute toxicity and safety, fermented deer antler at the respective doses of 0(control group), 2560, 3200, 4000 and 5000 mg/kg were given orally to 25 male ICR mice for 14 days and allocated 5 mice for each group. After a single administration of fermented deer antler extract, we observed survival rates, general toxicity and any changes in body weight. Autopsies were conducted on all 25 mice.
Results : Compared with the control group, we did not find any toxic alterations in any of the treated groups.
Conclusions : A single dose of 5000 mg/kg of fermented deer antler extract was found to be safe in ICR mice. However, anything beyond this level has the potential to be lethal.
KW - Deer Antler;Fermentation;Acute toxicity;Safety;LD50
DO -
UR -
ER -
Chung Won Suk, Kim Sung-Soo, oh jaekeun, LEE JUN HWAN, Kim Koh-Woon, 박현건, 최효정 and Jongsoo Lee. (2012). Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice. Journal of Korean Medicine Rehabilitation, 22(1), 1-10.
Chung Won Suk, Kim Sung-Soo, oh jaekeun, LEE JUN HWAN, Kim Koh-Woon, 박현건, 최효정 and Jongsoo Lee. 2012, "Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice", Journal of Korean Medicine Rehabilitation, vol.22, no.1 pp.1-10.
Chung Won Suk, Kim Sung-Soo, oh jaekeun, LEE JUN HWAN, Kim Koh-Woon, 박현건, 최효정, Jongsoo Lee "Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice" Journal of Korean Medicine Rehabilitation 22.1 pp.1-10 (2012) : 1.
Chung Won Suk, Kim Sung-Soo, oh jaekeun, LEE JUN HWAN, Kim Koh-Woon, 박현건, 최효정, Jongsoo Lee. Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice. 2012; 22(1), 1-10.
Chung Won Suk, Kim Sung-Soo, oh jaekeun, LEE JUN HWAN, Kim Koh-Woon, 박현건, 최효정 and Jongsoo Lee. "Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice" Journal of Korean Medicine Rehabilitation 22, no.1 (2012) : 1-10.
Chung Won Suk; Kim Sung-Soo; oh jaekeun; LEE JUN HWAN; Kim Koh-Woon; 박현건; 최효정; Jongsoo Lee. Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice. Journal of Korean Medicine Rehabilitation, 22(1), 1-10.
Chung Won Suk; Kim Sung-Soo; oh jaekeun; LEE JUN HWAN; Kim Koh-Woon; 박현건; 최효정; Jongsoo Lee. Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice. Journal of Korean Medicine Rehabilitation. 2012; 22(1) 1-10.
Chung Won Suk, Kim Sung-Soo, oh jaekeun, LEE JUN HWAN, Kim Koh-Woon, 박현건, 최효정, Jongsoo Lee. Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice. 2012; 22(1), 1-10.
Chung Won Suk, Kim Sung-Soo, oh jaekeun, LEE JUN HWAN, Kim Koh-Woon, 박현건, 최효정 and Jongsoo Lee. "Acute Toxicity of Fermented Deer Velvet Antler Extract in ICR Mice" Journal of Korean Medicine Rehabilitation 22, no.1 (2012) : 1-10.