본문 바로가기
  • Home

Comparison of Ingredients and Activities of Danggwisoo-san and Jakyakgamcho-tang by Extraction Method

  • Journal of Korean Medicine Rehabilitation
  • Abbr : JKMR
  • 2020, 30(4), pp.31-39
  • DOI : 10.18325/jkmr.2020.30.4.31
  • Publisher : The Korean Academy Of Oriental Rehabilitation Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : September 6, 2020
  • Accepted : September 24, 2020
  • Published : October 31, 2020

Dae-Yeon Lee 1 Ho-Sung Lee 2 Ju-hwi Jo 3 Young-woo Yi 3 Sung-Jin Kim 4 Kyungrae Kang 4 Tae-Wook Kwon 4 Seung Gu Yang 5 Lee In Hee 1

1㈜더포레, 포레스트한방병원
2㈜더포레
3포레스트 한방병원
4포레스트한방병원
5경희나로한방병원

Accredited

ABSTRACT

Objectives Danggwisoo-san and Jakyakgamcho-tang are frequently prescribed for traffic accident patients in Korea. The aim of this study was to examine index compound analysis, antioxidant activity and amount of starch measurement by extraction method. Methods Danggwisoo-san and Jakyakgamcho-tang were extracted with water and 70% ethanol. Antioxidant activity was measured by 2,2-Diphenyl-1-picrylhydrazyl, 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and ferric reducing antioxidant power according to the standard protocol. The contents of the indicator components nodakenin, paeoniflorin, and glycyrrhizin were measured by high-performance liquid chromatography, respectively. All starches were hydrolyzed and then total D-glucose was measured and compared. Results Antioxidant activity was excellent in 70% ethanol in all assays. The index component was jagged because its solubility was different depending on the extraction solvent. Starch content was significantly lower in 70% alcohol extract than water extract. Conclusions The results of this study showed that physiological activities and components are different according to extraction conditions. Each herbal medicine has a suitable extraction solvent. Also, the difference in starch content is an object to be considered as it may affect digestion and absorption. (J Korean Med Rehabil 2020;30(4):31-39)

Citation status

* References for papers published after 2022 are currently being built.